Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran.
Surg Infect (Larchmt). 2024 Sep;25(7):538-545. doi: 10.1089/sur.2024.090. Epub 2024 Aug 12.
Diarrheal illness is a prominent public health worry in developing countries, resulting in high mortality among children. Sociodemographic characteristics and geographic settings are the main effective factors for the increased incidence of childhood diarrhea. is a neglected organism capable of causing dysentery and diarrhea. The aim of this systematic review and meta-analysis was to determine the prevalence of as an agent in the causation of diarrhea in Asian children. We conducted a systematic review using Web of Science, PubMed, Wiley Online Library, Science Direct, and Google Scholar for peer-reviewed articles published between January 2000 and February 2023. We considered studies that found in diarrheal stool. A random-effects model was used to determine the pooled prevalence of . Our search returned 2,057 articles, with 17 articles from seven Asian nations being included in the systematic review. The pooled prevalence of was 4.5% (95% confidence interval [CI]: 2.9%-6.8%), with heterogeneity ( = 96.85; p < 0.001). There was a greater prevalence in areas with high population living in poverty (12.2%; 95% CI: 5.8%-24%) and lower-middle-income countries (5.0%; 95% CI: 2.7%-9.0%). In addition, the prevalence of was greater in South Asia (10.0%; 95% CI: 5.6%-17.2%), in India (12.9%; 95% CI: 6.8%-23%), and in countries with open defecation rate of 5%-25% (11.3%; 95% CI: 6.3%-19.2%). The prevalence of -associated diarrhea in children in Asia estimated in the present study highlighted the high burden of in some parts of Asia.
腹泻病是发展中国家突出的公共卫生问题，导致儿童死亡率居高不下。社会人口特征和地理环境是导致儿童腹泻发病率上升的主要影响因素。是一种被忽视的生物体，能够引起痢疾和腹泻。本系统评价和荟萃分析的目的是确定作为亚洲儿童腹泻病因的发生率。我们使用 Web of Science、PubMed、Wiley Online Library、Science Direct 和 Google Scholar 进行了系统评价，检索了 2000 年 1 月至 2023 年 2 月发表的同行评议文章。我们考虑了发现腹泻粪便中有 的研究。使用随机效应模型确定 的合并患病率。我们的搜索返回了 2057 篇文章，其中来自七个亚洲国家的 17 篇文章被纳入系统评价。 的合并患病率为 4.5%（95%置信区间 [CI]：2.9%-6.8%），异质性较大（ = 96.85；p < 0.001）。在人口中贫困人口比例较高（12.2%；95%CI：5.8%-24%）和中低收入国家（5.0%；95%CI：2.7%-9.0%）的地区，患病率更高。此外，南亚（10.0%；95%CI：5.6%-17.2%）、印度（12.9%；95%CI：6.8%-23%）和露天排便率为 5%-25%的国家（11.3%；95%CI：6.3%-19.2%）的患病率更高。本研究估计亚洲儿童中与相关的腹泻患病率突出了亚洲部分地区 的高负担。
