Ogurtsov R P, Zubzhitskii Iu N
Biull Eksp Biol Med. 1979 Dec;88(12):695-8.
Antibodies interacting with spermatid structures in the testis sections and with acrosome and caudal regions of spermatozoa in the smears of sperm were determined in the sera of guinea pigs and mice with experimental autoimmune orchitis by the indirect immunofluorescent method. The antibodies were found in mice from the 14th to the 30th day and in guinea pigs from the 14th to the 60th day after immunization. Circulation time and the level of the fluorescent antibodies were significantly decreased in immunized female guinea pigs and mice. Fluorescent antibodies did not show cytotoxic effect and belonged to the IgG fraction. The fluorescent antibodies of guinea pigs did not react with the mouse testicular antigens in cross reaction. The analogous results were seen in the cross reaction of the mouse antibodies with the guinea pig antigens.
采用间接免疫荧光法，在患有实验性自身免疫性睾丸炎的豚鼠和小鼠血清中，测定与睾丸切片中的精子细胞结构以及精子涂片顶体和尾部区域相互作用的抗体。在免疫后的第14天至第30天的小鼠以及第14天至第60天的豚鼠中发现了这些抗体。免疫后的雌性豚鼠和小鼠中，荧光抗体的循环时间和水平显著降低。荧光抗体未显示出细胞毒性作用，且属于IgG组分。豚鼠的荧光抗体在交叉反应中不与小鼠睾丸抗原发生反应。小鼠抗体与豚鼠抗原的交叉反应中也观察到类似结果。
