Pottier Morgane, Servier Jean-Marie, Migliore Vincent, Thirion Thierry, Nikkels Arjen
Service d'Orthopédie, CHU Liège, Belgique.
Service d'Orthopédie, CHR Mons, Belgique.
Rev Med Liege. 2024 Jul;79(7-8):521-526.
Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis. Half of the cases are associated with an immune dysfunction and are frequently triggered by pathergy such as a tissular aggression via surgery or burn wounds. A patient with ulcerative colitis presented a PG at the site of an iontophoresis patch for tendinopathy. Treatment in a specialized burn center, corticosteroid therapy and adapted local care contributed to a favourable evolution. PG remains a diagnosis of exclusion and inflammatory phenomena must be differentiated from infectious causes such as necrotizing fasciitis to initiate immunosuppressive treatment. Being rare and difficult to diagnose and to treat as well as associated with potentially severe sequelae, a multidisciplinary team is required for the management of PG.
坏疽性脓皮病（PG）是一种罕见的嗜中性皮病。半数病例与免疫功能障碍有关，常由同形反应触发，如手术或烧伤创面等组织损伤。一名溃疡性结肠炎患者在用于肌腱病的离子导入贴片部位出现了坏疽性脓皮病。在专业烧伤中心进行治疗、皮质类固醇疗法及适当的局部护理促使病情向好的方向发展。坏疽性脓皮病仍是一种排除性诊断，必须将炎症现象与坏死性筋膜炎等感染性病因相鉴别，以便开始免疫抑制治疗。由于坏疽性脓皮病罕见、诊断和治疗困难且伴有潜在的严重后遗症，因此需要多学科团队来管理该病。
