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孕期抗逆转录病毒暴露的安全性:填补数据空白的机遇

Safety of Antiretroviral Exposure During Pregnancy: Opportunities to Close Data Gaps.

作者信息

Short William R, Miller Emily S, Simone Joanne, Statton Anne, Finocchario-Kessler Sarah, Lampe Margaret

机构信息

Department of Medicine, Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Alpert Medical School of Brown University, Providence, Rhode Island, USA.

出版信息

Open Forum Infect Dis. 2024 Jul 23;11(8):ofae423. doi: 10.1093/ofid/ofae423. eCollection 2024 Aug.

DOI:10.1093/ofid/ofae423
PMID:39130080
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11310583/
Abstract

Pregnant persons with chronic health conditions often require pharmacotherapy to remain healthy. The Antiretroviral Pregnancy Registry is a prospective, international, voluntary, and exposure registry that collects information on antiretroviral (ARV) exposure; however, a minority of providers use the registry, leaving critical gaps to guide prescribing in this population. The Task Force for the Elimination of Perinatal HIV Transmission in the United States, funded by the Centers for Disease Control and Prevention, has identified the monitoring of ARV safety as a paramount concern in the ongoing mission to eliminate perinatal human immunodeficiency virus (HIV) transmission. As active members of this task force, we urge all healthcare providers who care for pregnant individuals to prioritize reporting all ARV exposures to the registry.

摘要

患有慢性健康状况的孕妇通常需要药物治疗来保持健康。抗逆转录病毒妊娠登记处是一个前瞻性、国际性、自愿性的暴露登记处,收集有关抗逆转录病毒(ARV)暴露的信息;然而,少数医疗服务提供者使用该登记处,导致在指导该人群用药方面存在关键空白。由疾病控制与预防中心资助的美国消除围产期HIV传播特别工作组已将监测抗逆转录病毒药物的安全性确定为正在进行的消除围产期人类免疫缺陷病毒(HIV)传播任务中的首要关注点。作为该特别工作组的积极成员,我们敦促所有为孕妇提供护理的医疗服务提供者将向登记处报告所有抗逆转录病毒药物暴露情况作为优先事项。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c83/11310583/3f1e52399ff5/ofae423f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c83/11310583/3f1e52399ff5/ofae423f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c83/11310583/3f1e52399ff5/ofae423f1.jpg

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本文引用的文献

1
Strengthening the Evidence: Similar Rates of Neural Tube Defects Among Deliveries Regardless of Maternal HIV Status and Dolutegravir Exposure in Hospital Birth Surveillance in Eswatini.强化证据:在斯威士兰的医院出生监测中,无论产妇的艾滋病毒感染状况和多替拉韦暴露情况如何,神经管缺陷的发生率相似。
Open Forum Infect Dis. 2023 Aug 18;10(9):ofad441. doi: 10.1093/ofid/ofad441. eCollection 2023 Sep.
2
Dolutegravir and pregnancy outcomes including neural tube defects in the USA during 2008-20: a national cohort study.2008-20 年美国多替拉韦与妊娠结局(包括神经管缺陷):一项全国队列研究。
Lancet HIV. 2023 Sep;10(9):e588-e596. doi: 10.1016/S2352-3018(23)00108-X. Epub 2023 Jul 25.
3
Importance of Prospective Studies in Pregnant and Breastfeeding Women Living With Human Immunodeficiency Virus.
患有人类免疫缺陷病毒的孕妇和哺乳期妇女进行前瞻性研究的重要性。
Clin Infect Dis. 2019 Sep 13;69(7):1254-1258. doi: 10.1093/cid/ciz121.
4
Neural-Tube Defects with Dolutegravir Treatment from the Time of Conception.受孕时使用多替拉韦治疗导致的神经管缺陷。
N Engl J Med. 2018 Sep 6;379(10):979-981. doi: 10.1056/NEJMc1807653. Epub 2018 Jul 24.
5
Safety of efavirenz in the first trimester of pregnancy: an updated systematic review and meta-analysis.妊娠早期依法韦仑的安全性:一项更新的系统评价和荟萃分析。
AIDS. 2014 Mar;28 Suppl 2:S123-31. doi: 10.1097/QAD.0000000000000231.
6
Pharmacotherapy and pregnancy: Highlights from the first International Conference for Individualized Pharmacotherapy in Pregnancy.药物治疗与妊娠:首届妊娠期个体化药物治疗国际会议亮点
Clin Transl Sci. 2009 Feb;2(1):11-4. doi: 10.1111/j.1752-8062.2009.00079.x.
7
Teratogenicity risk of antiretroviral therapy in pregnancy.孕期抗逆转录病毒疗法的致畸风险。
Curr HIV/AIDS Rep. 2007 Aug;4(3):135-40. doi: 10.1007/s11904-007-0020-y.
8
Utilization of animal studies to determine the effects and human risks of environmental toxicants (drugs, chemicals, and physical agents).利用动物研究来确定环境毒物(药物、化学物质和物理因子)的影响及对人类的风险。
Pediatrics. 2004 Apr;113(4 Suppl):984-95.
9
Periconceptional exposure to efavirenz and neural tube defects.受孕前后接触依非韦伦与神经管缺陷
Arch Intern Med. 2002 Feb 11;162(3):355. doi: 10.1001/archinte.162.3.355.
10
Myelomeningocele in a child with intrauterine exposure to efavirenz.一名在子宫内接触过依非韦伦的儿童患有的脊髓脊膜膨出。
AIDS. 2002 Jan 25;16(2):299-300. doi: 10.1097/00002030-200201250-00025.