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使用脚踝外骨骼在真实地形上行走对脑瘫患者的影响

Walking on Real-world Terrain with an Ankle Exoskeleton in Cerebral Palsy.

作者信息

Tagoe Emmanuella A, Fang Ying, Williams Jack R, Lerner Zachary F

机构信息

Department of Mechanical Engineering, Northern Arizona University; Flagstaff, AZ, USA.

Department of Mechanical Engineering, Northern Arizona University, Flagstaff, AZ, USA. She is now with the Rosalind Franklin University, North Chicago, IL USA.

出版信息

IEEE Trans Med Robot Bionics. 2024 Feb;6(1):202-212. doi: 10.1109/tmrb.2023.3328649. Epub 2023 Oct 31.

DOI:10.1109/tmrb.2023.3328649
PMID:39130167
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11309519/
Abstract

Despite medical treatment focused on addressing walking disability, many millions of people with neurological conditions, like cerebral palsy (CP), struggle to maintain independent mobility. Lower limb exoskeletons and exosuits may hold potential for augmenting walking ability. However, it remains unknown whether these wearable robots are safe and beneficial for use outside of highly controlled laboratory environments, the demonstration of which is necessary for clinical translation. Here, we show that a lightweight, portable, ankle exoskeleton with an adaptable one-size-works-for-all assistance controller can improve energy efficiency and walking speed for individuals with CP spanning a wide spectrum of lower limb impairment in a multi-terrain real-world environment. Tested on an outdoor walking route with level, sloped, and stair terrain, robotic assistance resulted in a 15-18% (p = 0.013-0.026) reduction in estimated energy cost and a 7-8% (p = 0.001-0.004) increase in average walking speed across "shorter" 6-minute and "longer" 20-minute walking durations relative to unassisted walking. This study provides evidence that wearable robots may soon improve mobility in neighborhood, school, and community settings for individuals with CP.

摘要

尽管针对行走障碍的医学治疗已受到关注,但数百万患有神经系统疾病(如脑瘫)的人仍难以保持独立行动能力。下肢外骨骼和外骨骼套装可能具有增强行走能力的潜力。然而,这些可穿戴机器人在高度受控的实验室环境之外使用是否安全且有益尚不清楚,而这一点对于临床转化是必要的。在此,我们展示了一种轻便、便携的脚踝外骨骼,其配备了适用于所有人的自适应辅助控制器,在多地形现实环境中,能够提高患有各种下肢损伤的脑瘫患者的能量效率和行走速度。在包含平地、斜坡和楼梯地形的户外行走路线上进行测试时,与无辅助行走相比,机器人辅助使“较短”6分钟和“较长”20分钟步行时长的估计能量消耗降低了15 - 18%(p = 0.013 - 0.026),平均行走速度提高了7 - 8%(p = 0.001 - 0.004)。这项研究提供了证据,表明可穿戴机器人可能很快就能改善脑瘫患者在邻里、学校和社区环境中的行动能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbc/11309519/13f8b8ec2a24/nihms-1963171-f0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbc/11309519/43f1931ff8e4/nihms-1963171-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbc/11309519/f3dee0f87378/nihms-1963171-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbc/11309519/6b0d0c8c76c0/nihms-1963171-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbc/11309519/3107750ada09/nihms-1963171-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbc/11309519/28502ef37862/nihms-1963171-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbc/11309519/13f8b8ec2a24/nihms-1963171-f0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbc/11309519/43f1931ff8e4/nihms-1963171-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbc/11309519/f3dee0f87378/nihms-1963171-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbc/11309519/6b0d0c8c76c0/nihms-1963171-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbc/11309519/3107750ada09/nihms-1963171-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbc/11309519/28502ef37862/nihms-1963171-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbc/11309519/13f8b8ec2a24/nihms-1963171-f0006.jpg

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Nat Biomed Eng. 2023 Apr;7(4):456-472. doi: 10.1038/s41551-022-00984-1. Epub 2022 Dec 22.
2
Personalizing exoskeleton assistance while walking in the real world.在现实世界中行走时实现外骨骼辅助的个性化定制。
Nature. 2022 Oct;610(7931):277-282. doi: 10.1038/s41586-022-05191-1. Epub 2022 Oct 12.
3
How Ankle Exoskeleton Assistance Affects the Mechanics of Incline Walking and Stair Ascent in Cerebral Palsy.
使用心率反馈的自适应髋部外骨骼控制可降低日常运动中的氧气消耗。
Sci Rep. 2025 Jan 2;15(1):507. doi: 10.1038/s41598-024-84253-y.
4
Exoskeleton gait training on real-world terrain improves spatiotemporal performance in cerebral palsy.在真实地形上进行外骨骼步态训练可改善脑瘫患者的时空运动表现。
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5
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IEEE Open J Eng Med Biol. 2024 Oct 8;6:75-81. doi: 10.1109/OJEMB.2024.3475911. eCollection 2025.
6
Task-agnostic exoskeleton control via biological joint moment estimation.通过生物关节力矩估计实现任务无关的外骨骼控制。
Nature. 2024 Nov;635(8038):337-344. doi: 10.1038/s41586-024-08157-7. Epub 2024 Nov 13.
7
Evaluation of the Working Mechanism of a Newly Developed Powered Ankle-Foot Orthosis.新型动力踝足矫形器工作机制的评估。
Sensors (Basel). 2024 Oct 11;24(20):6562. doi: 10.3390/s24206562.
踝部外骨骼助力如何影响脑瘫患者斜行和楼梯上升的力学。
IEEE Int Conf Rehabil Robot. 2022 Jul;2022:1-6. doi: 10.1109/ICORR55369.2022.9896476.
4
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8
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