Karthikeyan Padmanabhan, Ashish Sharad
Department of ENT, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Pondicherry, India.
Indian J Otolaryngol Head Neck Surg. 2024 Aug;76(4):3617-3620. doi: 10.1007/s12070-024-04640-9. Epub 2024 Mar 25.
Tumors in the nasal septum originating from salivary glands are uncommon, and among them, pleomorphic adenomas represent a distinctive manifestation.This case study explores a female in her early thirties with a right-sided nasal mass, nasal obstruction, and intermittent bleeding. CT imaging revealed a lesion arising from the nasal septum with bony erosion. Histopathology confirmed pleomorphic adenoma,emphasizing the importance of thorough clinical evaluation, imaging, and biopsy for accurate diagnosis. Pleomorphic adenomas, typically found in major salivary glands, can occur in the respiratory tract, presenting challenges in distinguishing them from malignant tumors. Treatment involves wide local resection, and postoperative recurrence may necessitate radiotherapy. While intranasal pleomorphic adenomas generally have a favorable prognosis, those arising from the nasal septum have an elevated likelihood of malignancy. Vigilant monitoring is crucial due to the potential for recurrence, malignant transformation, and metastasis.
起源于唾液腺的鼻中隔肿瘤并不常见,其中多形性腺瘤是一种独特的表现形式。本病例研究探讨了一名三十出头的女性,她患有右侧鼻腔肿物、鼻塞和间歇性出血。CT成像显示鼻中隔有一处病变并伴有骨质侵蚀。组织病理学确诊为多形性腺瘤,强调了全面临床评估、影像学检查和活检对于准确诊断的重要性。多形性腺瘤通常见于大唾液腺,也可发生于呼吸道,这给将其与恶性肿瘤区分开来带来了挑战。治疗方法包括广泛局部切除,术后复发可能需要放疗。虽然鼻内多形性腺瘤总体预后良好,但起源于鼻中隔的多形性腺瘤恶变可能性增加。由于存在复发、恶变和转移的可能性,严密监测至关重要。