Itogawa Katsuhiro, Oba Tomohiro, Maki Mitsuru, Amano Masako, Adachi Akiko, Matsushima Hidekazu
Department of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan.
Department of Thoracic Surgery, Saitama Red Cross Hospital, Saitama, Japan.
Respir Med Case Rep. 2025 Jul 2;57:102253. doi: 10.1016/j.rmcr.2025.102253. eCollection 2025.
Tracheobronchial tumor is a relatively uncommon type of respiratory tumor. Seromucous gland tumors, such as adenoid cystic carcinoma, mucoepidermoid carcinoma, and pleomorphic adenoma, are a part of this category. Among them, pleomorphic adenoma is especially rare. This report describes a case of bronchial pleomorphic adenoma successfully diagnosed and removed with surgery. A 70-year-old Japanese man presented with abnormal chest shadow and intermittent fever. A subsequently conducted chest computed tomography revealed a 40mm-sized mass in the left lower bronchus and distal obstructive pneumonia. Because a transbronchial biopsy was not diagnostic, a left lower sleeve lobectomy was performed. As a result, the mass was completely resected and a diagnosis of pleomorphic adenoma was made. Treatment options for pleomorphic adenoma include surgery and endoscopic resection, because observation is sometimes inadvisable due to the risk of metastasis or malignant transformation. Furthermore, complete resection is diagnostically appropriate because pleomorphic adenoma is sometimes undiagnosed or misdiagnosed with partially resected or biopsied specimen, due to the heterogeneity in pathology. This case underscores the challenges in diagnosing pleomorphic adenoma and highlights the importance of complete surgical resection for definitive diagnosis and treatment.
气管支气管肿瘤是一种相对罕见的呼吸道肿瘤。血清黏液腺肿瘤,如腺样囊性癌、黏液表皮样癌和多形性腺瘤,属于这一类别。其中,多形性腺瘤尤为罕见。本报告描述了一例成功诊断并通过手术切除的支气管多形性腺瘤病例。一名70岁的日本男性出现胸部阴影异常和间歇性发热。随后进行的胸部计算机断层扫描显示左肺下叶支气管有一个40毫米大小的肿块及远端阻塞性肺炎。由于经支气管活检未能明确诊断,遂行左肺下叶袖状肺叶切除术。结果,肿块被完全切除,并诊断为多形性腺瘤。多形性腺瘤的治疗选择包括手术和内镜切除,因为由于存在转移或恶变风险,有时观察并不可取。此外,由于病理的异质性,多形性腺瘤有时在部分切除或活检标本时无法诊断或被误诊,因此完整切除在诊断上是合适的。该病例强调了多形性腺瘤诊断中的挑战,并突出了完整手术切除对于明确诊断和治疗的重要性。