Pierin Ely G, Sassi Laurindo M, Schussel Juliana L
Post-graduation Program in Dentistry, Department of Stomatology, Universidade Federal do Paraná.
DDS MSc PhD. Department of Oral and Maxillofacial Surgery, Erasto Gaerner Cancer Center.
J Clin Exp Dent. 2024 Jun 1;16(6):e666-e669. doi: 10.4317/jced.61590. eCollection 2024 Jun.
Actinic cheilitis (AC), an oral potentially malignant oral disorder (OPMD), predominantly affects fair-skinned individuals, particularly males, with a higher prevalence in their sixth and seventh decades. In the Southeast region of Brazil, oral cancer ranks as the fourth most common tumor among males, with squamous cell carcinoma (SCC) constituting 90% to 95% of lip tumor cases, primarily impacting the lower lip. This retrospective study aims to evaluate the malignant transformation rate in previously diagnosed AC patients between 2008 and 2018, utilizing biopsy records.
We retrospectively reviewed medical records of lip lesion patients at the Department of Oral and Maxillofacial Surgery (DOMS) during the stated period, collecting demographic and medical data for analysis.
Among the 224 analyzed AC cases, 67.8% were male, with an average age of 65 years. Approximately 87.6% of patients reported occupational exposure to AC-associated risk factors. Malignant transformations occurred in 27 patients (12.05%).
Our study underscores the possible effect of early intervention and preventive measures in stabilizing AC lesions and averting their progression to malignancy. These findings underscore the significance of prompt AC diagnosis and management to mitigate the risk of malignant transformation. Actinic cheilitis, oral squamous cell carcinoma, malignant transformation.
光化性唇炎（AC）是一种口腔潜在恶性疾病（OPMD），主要影响皮肤白皙的个体，尤其是男性，在60和70岁人群中患病率更高。在巴西东南部地区，口腔癌是男性中第四大常见肿瘤，鳞状细胞癌（SCC）占唇部肿瘤病例的90%至95%，主要影响下唇。本回顾性研究旨在利用活检记录评估2008年至2018年期间先前诊断为AC的患者的恶性转化率。
我们回顾性分析了所述期间口腔颌面外科（DOMS）唇部病变患者的病历，收集人口统计学和医学数据进行分析。
在224例分析的AC病例中，67.8%为男性，平均年龄65岁。约87.6%的患者报告有职业性接触AC相关危险因素。27例（12.05%）发生了恶性转化。
我们的研究强调了早期干预和预防措施在稳定AC病变及避免其进展为恶性病变方面的可能作用。这些发现强调了及时诊断和管理AC以降低恶性转化风险的重要性。光化性唇炎、口腔鳞状细胞癌、恶性转化。
