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新型冠状病毒肺炎感染引发特发性毛细血管渗漏综合征,采用ECMELLA治疗。

COVID-19 infection triggered idiopathic capillary leak syndrome treated with ECMELLA.

作者信息

Wester Michael, Drasch Thomas, Schneckenpointner Roland, Foltan Maik, Philipp Alois, Müller Thomas, Banas Bernhard, Maier Lars S, Matthias Lubnow P D

机构信息

University Heart Centre Regensburg, Department of Internal Medicine II, University Hospital of Regensburg, Regensburg, Germany.

Department of Nephrology, University Hospital of Regensburg, Regensburg, Germany.

出版信息

Heliyon. 2024 Jul 16;10(14):e34693. doi: 10.1016/j.heliyon.2024.e34693. eCollection 2024 Jul 30.

Abstract

BACKGROUND

Idiopathic systemic capillary leak syndrome (ISCLS) is characterized by recurrent systemic capillary leakage and hypovolemic shock.

CASE PRESENTATION

We report a 59-year-old Caucasian man with ISCLS and persistent hypovolemic and cardiogenic shock after COVID-19 infection. Mechanical circulatory support was provided with veno-arterial extracorporeal membrane oxygenation and a microaxial pump. Massive fluid resuscitation was needed. Subsequent complications prolonged the intensive care treatment. Mechanical circulatory support was needed for 22 days. Cardiac function eventually fully recovered, and the patient survived without neurologic compromise.

CONCLUSIONS

This case of severe ISCLS triggered by COVID-19 highlights that even the most severe hypovolemic and cardiogenic shock may be reversible in ISCLS.

摘要

背景

特发性系统性毛细血管渗漏综合征(ISCLS)的特征是反复出现全身性毛细血管渗漏和低血容量性休克。

病例介绍

我们报告了一名59岁的白人男性,患有ISCLS,在感染COVID-19后出现持续性低血容量性和心源性休克。通过静脉-动脉体外膜肺氧合和微型轴流泵提供机械循环支持。需要大量液体复苏。随后的并发症延长了重症监护治疗时间。机械循环支持需要22天。心脏功能最终完全恢复,患者存活且无神经功能损害。

结论

该例由COVID-19引发的严重ISCLS突出表明,即使是最严重的低血容量性和心源性休克在ISCLS中也可能是可逆的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2cc/11315138/476697b34cce/gr1.jpg

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