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四叶式主动脉瓣:一例疑似心内膜炎及处理的罕见病例

Quadricuspid Aortic Valve: A Rare Case of Endocarditis Suspicion and Management.

作者信息

Olaniyi Seyi A, Saidu Anne, Arowolo Seun, Sam Alen, Omeh Chinyere K, Ali Sofia, Khan Misbah Kamal

机构信息

Medicine and Surgery, Obafemi Awolowo University, Ile Ife, NGA.

Medicine, V.N. Karazin Kharkiv National University, Kharkiv, UKR.

出版信息

Cureus. 2024 Jul 12;16(7):e64419. doi: 10.7759/cureus.64419. eCollection 2024 Jul.

Abstract

Quadricuspid aortic valve (QAV), a rare congenital cardiac anomaly, often presents with aortic regurgitation and can lead to significant cardiovascular complications. This case report describes a 55-year-old male with a history of subarachnoid hemorrhage who was incidentally found to have QAV with possible endocarditis. Transesophageal echocardiography revealed thickened leaflet tips on all four cusps and a mass on one leaflet, raising suspicion of endocarditis despite the absence of vegetation. The patient was treated with intravenous antibiotics for Gram-positive bacteremia, and follow-up imaging confirmed the QAV anomaly with moderate aortic regurgitation. This case highlights the challenges in diagnosing QAV, particularly in asymptomatic individuals, and underscores the need for comprehensive investigation, especially in those with a history of vascular events. It also emphasizes the importance of further research to clarify the long-term risks and optimal management strategies for individuals with QAV, including the potential for infective endocarditis.

摘要

四叶式主动脉瓣(QAV)是一种罕见的先天性心脏异常,常伴有主动脉反流,并可导致严重的心血管并发症。本病例报告描述了一名55岁男性,有蛛网膜下腔出血病史,偶然发现患有QAV且可能合并心内膜炎。经食管超声心动图显示所有四个瓣叶的瓣叶尖端增厚,一个瓣叶上有一个肿块,尽管没有赘生物,但仍怀疑有心内膜炎。该患者因革兰氏阳性菌血症接受了静脉抗生素治疗,后续影像学检查证实了QAV异常并伴有中度主动脉反流。本病例突出了诊断QAV的挑战,尤其是在无症状个体中,并强调了进行全面检查的必要性,特别是对于有血管事件病史的个体。它还强调了进一步研究以阐明QAV患者的长期风险和最佳管理策略的重要性,包括感染性心内膜炎的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9a3/11317075/8dd579619e3e/cureus-0016-00000064419-i01.jpg

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