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基于蒙特卡罗方法的热释光剂量计在治疗性质子和碳离子束中吸收剂量能量依赖性的研究

Monte Carlo-based Investigation of Absorbed-dose Energy Dependence of Thermoluminescent Dosimeters in Therapeutic Proton and Carbon Ion Beams.

作者信息

Chattaraj Arghya, Mishra Subhalaxmi, Selvam T Palani

机构信息

Radiological Physics and Advisory Division, Health, Safety and Environment Group, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India.

Homi Bhabha National Institute, Mumbai, Maharashtra, India.

出版信息

J Med Phys. 2024 Apr-Jun;49(2):148-154. doi: 10.4103/jmp.jmp_25_24. Epub 2024 Jun 25.

DOI:10.4103/jmp.jmp_25_24
PMID:39131434
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11309140/
Abstract

BACKGROUND

The present study is aimed at calculating relative absorbed-dose energy response correction () of commonly used thermoluminescent dosimeters (TLDs) such as LiF, LiBO, and AlO as a function of depth in water for protons (50-250 MeV/n) and carbon ion (80-480 MeV/n) beams using Monte Carlo-based FLUKA code.

MATERIALS AND METHODS

On-axis depth-dose profiles in water are calculated for protons (50-250 MeV/n) and carbon ion (80-480 MeV/n) beams using FLUKA code. For the calculation of , selective depths are chosen based on the depth-dose profiles. In the simulations, the TLDs of dimensions 1 mm × 1 mm × 1 mm are positioned at the flat, dose gradient, and Bragg peak regions of the depth-dose profile. Absorbed dose to detector was calculated within the TLD material. In the second step, TLD voxels were replaced by water voxel of similar dimension and absorbed dose to water was scored.

RESULTS

The study reveals that for both proton and carbon ion beams, the value of differs from unity significantly at the Bragg peak position and is close to unity at the flat region for the investigated TLDs. The calculated value is sensitive to depth in water, beam energy, type of ion beam, and type of TLD.

DISCUSSION

For accurate dosimetry of protons and carbon ion beams using TLDs, the response of the TLD should be corrected to account for its absorbed-dose energy dependence.

摘要

背景

本研究旨在使用基于蒙特卡罗的FLUKA代码，计算常用热释光剂量计（TLD）（如LiF、LiBO和AlO）的相对吸收剂量能量响应校正（），作为质子（50 - 250 MeV/n）和碳离子（80 - 480 MeV/n）束在水中深度的函数。

材料与方法

使用FLUKA代码计算质子（50 - 250 MeV/n）和碳离子（80 - 480 MeV/n）束在水中的轴上深度剂量分布。为了计算，根据深度剂量分布选择特定深度。在模拟中，尺寸为1 mm×1 mm×1 mm的TLD放置在深度剂量分布的平坦、剂量梯度和布拉格峰区域。在TLD材料内计算探测器的吸收剂量。第二步，将TLD体素替换为尺寸相似的水体素，并计算水的吸收剂量。

结果

研究表明，对于质子束和碳离子束，在所研究的TLD中，在布拉格峰位置的值显著不同于1，在平坦区域接近1。计算得到的值对水中深度、束能量、离子束类型和TLD类型敏感。

讨论

为了使用TLD对质子束和碳离子束进行准确的剂量测定，应校正TLD的响应，以考虑其吸收剂量能量依赖性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0413/11309140/dd3640b1dcff/JMP-49-148-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0413/11309140/275127efe18c/JMP-49-148-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0413/11309140/d866a38abb40/JMP-49-148-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0413/11309140/59aa5286fe57/JMP-49-148-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0413/11309140/5df27a044f6e/JMP-49-148-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0413/11309140/dd3640b1dcff/JMP-49-148-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0413/11309140/275127efe18c/JMP-49-148-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0413/11309140/d866a38abb40/JMP-49-148-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0413/11309140/59aa5286fe57/JMP-49-148-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0413/11309140/5df27a044f6e/JMP-49-148-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0413/11309140/dd3640b1dcff/JMP-49-148-g011.jpg

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