质子治疗的物理学原理。
The physics of proton therapy.
作者信息
Newhauser Wayne D, Zhang Rui
机构信息
Medical Physics Program, Department of Physics and Astronomy, Louisiana State University, 202 Nicholson Hall, Baton Rouge, LA 70803, USA. Mary Bird Perkins Cancer Center, 4950 Essen Lane, Baton Rouge, LA 70809, USA.
出版信息
Phys Med Biol. 2015 Apr 21;60(8):R155-209. doi: 10.1088/0031-9155/60/8/R155. Epub 2015 Mar 24.
Abstract
The physics of proton therapy has advanced considerably since it was proposed in 1946. Today analytical equations and numerical simulation methods are available to predict and characterize many aspects of proton therapy. This article reviews the basic aspects of the physics of proton therapy, including proton interaction mechanisms, proton transport calculations, the determination of dose from therapeutic and stray radiations, and shielding design. The article discusses underlying processes as well as selected practical experimental and theoretical methods. We conclude by briefly speculating on possible future areas of research of relevance to the physics of proton therapy.
摘要
自1946年质子治疗被提出以来，其物理学原理已经有了长足的发展。如今，解析方程和数值模拟方法可用于预测和描述质子治疗的许多方面。本文回顾了质子治疗物理学的基本方面，包括质子相互作用机制、质子输运计算、治疗辐射和杂散辐射剂量的确定以及屏蔽设计。本文讨论了潜在过程以及一些实用的实验和理论方法。我们最后简要推测了与质子治疗物理学相关的未来可能的研究领域。
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