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供者评估工具:一项新技术提高 ICU 供者招募。

Donor Evaluation Tool: A New Technology Improves Donor Enrolment on ICU.

机构信息

Swisstransplant, National Foundation for Organ Donation and Transplantation, Bern, Switzerland.

出版信息

Transpl Int. 2024 Jul 26;37:12227. doi: 10.3389/ti.2024.12227. eCollection 2024.

DOI:10.3389/ti.2024.12227
PMID:39131790
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11310011/
Abstract

Uncertainties on the intensive care unit (ICU) regarding the eligibility of a patient to be a potential deceased organ donor may prevent their referral and enrolment in the pathway for organ donation. Healthcare staff may exclude potential donors for medical reasons, which are no longer applicable. Hence, Swisstransplant implemented a digital donor evaluation tool (DET) in 2021, which allows the local hospital's organ donation coordinator to send a direct request to medical advisors (MA) of the organ procurement organization before excluding potential donors. All 156 requests entered in 2022 were analyzed. 117 patients (75.0%) were primarily accepted by the MA as potential donors. Of those 60 patients (51.3%) became actual organ donors. Main reasons for using the DET were questions regarding malignancies (n = 33, 21.2%), infectious diseases (n = 35, 22.4%) and age/co-morbidities (n = 34, 21.8%). The average age of the actual "DET donor" compared to the regularly enrolled, actual "Non-DET donor" was 65.3 ± 15.8 vs. 56.8 ± 17.5 years, respectively ( = 0.008). On average 1.9 ± 1.1 organs compared to 3.2 ± 1.3 organs were retrieved from DET vs. Non-DET donors. In summary, this new digital donor evaluation tool supports reporting and facilitates eligibility decisions in uncertain, complex donor cases, potentially increasing the number of organ donations.

摘要

在重症监护病房 (ICU),由于对患者是否有资格成为潜在的已故器官捐献者存在不确定性,可能会导致他们无法被转介并纳入器官捐献途径。医护人员可能会因为不再适用的医疗原因而排除潜在的捐献者。因此,瑞士器官移植组织 (Swisstransplant) 于 2021 年推出了数字器官捐献评估工具 (DET),允许当地医院的器官捐献协调员在排除潜在捐献者之前,直接向器官获取组织的医学顾问 (MA) 发送请求。2022 年共分析了 156 份请求。MA 初步接受了 117 名患者 (75.0%) 作为潜在的捐献者。其中 60 名患者 (51.3%) 最终成为实际的器官捐献者。使用 DET 的主要原因是关于恶性肿瘤 (n = 33, 21.2%)、传染病 (n = 35, 22.4%) 和年龄/合并症 (n = 34, 21.8%) 的问题。与常规登记的实际“非 DET 捐献者”相比,实际“DET 捐献者”的平均年龄为 65.3 ± 15.8 岁对 56.8 ± 17.5 岁(= 0.008)。与非 DET 捐献者相比,从 DET 捐献者中平均可获取 1.9 ± 1.1 个器官对 3.2 ± 1.3 个器官。总之,这种新的数字器官捐献评估工具支持报告,并在不确定和复杂的捐献者情况下促进资格决策,有可能增加器官捐献的数量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/069c/11310011/29f89b94d95e/ti-37-12227-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/069c/11310011/593c8be7e1b5/ti-37-12227-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/069c/11310011/15b1af943bd9/ti-37-12227-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/069c/11310011/29f89b94d95e/ti-37-12227-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/069c/11310011/593c8be7e1b5/ti-37-12227-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/069c/11310011/15b1af943bd9/ti-37-12227-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/069c/11310011/29f89b94d95e/ti-37-12227-g003.jpg

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本文引用的文献

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Lancet Public Health. 2021 Oct;6(10):e709-e719. doi: 10.1016/S2468-2667(21)00200-0. Epub 2021 Aug 30.
2
In the eye of the hurricane: the Swiss COVID-19 pandemic stepwise shutdown approach in organ donation and transplantation.在飓风眼中:瑞士 COVID-19 大流行分阶段关闭器官捐献和移植的方法。
Swiss Med Wkly. 2020 Dec 31;150:w20447. doi: 10.4414/smw.2020.20447. eCollection 2020 Dec 14.
3
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器官利用 - 移植的下一个障碍?
Transpl Int. 2020 Dec;33(12):1597-1609. doi: 10.1111/tri.13744. Epub 2020 Oct 5.
4
Ten years of donor-derived disease: A report of the disease transmission advisory committee.十年的供体源性疾病:疾病传播咨询委员会报告
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Clin Transplant. 2019 Nov;33(11):e13711. doi: 10.1111/ctr.13711. Epub 2019 Sep 25.
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Transpl Int. 2020 Jan;33(1):76-88. doi: 10.1111/tri.13506. Epub 2019 Oct 7.
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Transplantation. 2018 Oct;102(10):1768-1778. doi: 10.1097/TP.0000000000002226.
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Swiss Med Wkly. 2015 Jan 14;145:w14062. doi: 10.4414/smw.2015.14062. eCollection 2015.
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