Hetzer R, Warnecke H, Oye G, Borst H G
Z Kardiol. 1985;74 Suppl 6:7-14.
Since 1968, the mitral valve was repaired, rather than replaced, in 647 patients. During the same period, 2,223 patients underwent prosthetic mitral replacement. Short and long-term results of mitral repair compare favorably with those after valve replacement. Five-year actuarial survival was 89% after closed commissurotomy (213 patients), 87% after open commissurotomy (203 patients) and 81% after more complex reconstructive procedures (231 patients). The operative risk was below 3% in all groups, the risk of reoperation was between 0.7% and 3%/patient year. Reconstruction was feasible in 16 patients with "floppy valve" syndrome, in 73 patients with ruptured chordae of the posterior leaflet and in 7 patients with bacterial endocarditis, with good long-term results in all of these patients. The feasibility of mitral reconstruction depends on the pliability of the anterior mitral leaflet, which may be decreased in mixed rheumatic lesions. In these patients, we would recommend prosthetic replacement of the valve. It is concluded that superior results may be achieved by mitral repair as compared to mitral replacement. However, indication and surgical technique largely depend upon the individual experience of the surgeon. The postoperative function of the reconstructed valve can be reliably assessed during the operation by left ventricular infusion of cold cardioplegic solution.
自1968年以来,647例患者接受了二尖瓣修复而非置换手术。同期,2223例患者接受了人工二尖瓣置换术。二尖瓣修复的短期和长期效果优于瓣膜置换术后的效果。闭式二尖瓣交界分离术(213例患者)后5年实际生存率为89%,直视二尖瓣交界分离术(203例患者)后为87%,更复杂的重建手术(231例患者)后为81%。所有组的手术风险均低于3%,再次手术风险为0.7%至3%/患者年。16例“瓣膜松弛”综合征患者、73例后叶腱索断裂患者和7例细菌性心内膜炎患者可行重建手术,所有这些患者均取得了良好的长期效果。二尖瓣重建的可行性取决于二尖瓣前叶的柔韧性,在混合性风湿性病变中其柔韧性可能降低。对于这些患者,我们建议进行瓣膜置换。结论是,与二尖瓣置换相比,二尖瓣修复可取得更好的效果。然而,适应症和手术技术很大程度上取决于外科医生的个人经验。术中通过向左心室输注冷心脏停搏液可可靠地评估重建瓣膜的术后功能。