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右冠状动脉手术期间医源性主动脉冠状动脉夹层:已发表文献的系统评价

Iatrogenic Aortocoronary Dissection During Right Coronary Artery Procedures: A Systematic Review of the Published Literature.

作者信息

Sanchez-Jimenez Erick, Levi Yaniv, Roguin Ariel

机构信息

Cardiology Department, Hillel Yaffe Medical Center, Hadera, Israel.

Technion - Israel Institute of Technology, Israel.

出版信息

J Soc Cardiovasc Angiogr Interv. 2022 Aug 27;1(6):100443. doi: 10.1016/j.jscai.2022.100443. eCollection 2022 Nov-Dec.

Abstract

Iatrogenic aortocoronary dissection (IACD) occurs mainly during procedures involving the right coronary artery (RCA) and can result in disabilities, the need for urgent complex surgery, and even death. The risk factors for IACD are ill characterized, and the best management strategy is questionable; thus, there is a need to evaluate the characteristics, treatment options, and outcomes of patients with IACD of the RCA. We searched medical databases for publications on IACD of the RCA to present the characteristics of the procedures, management, and outcomes. We report 142 cases of IACD of the RCA, reported between 1973 and 2021. The mean age of the patients was 63.0 years, 81 (57%) were men, 75 (52.8%) presented with stable angina, and 29 (20.4%) had chronic total occlusion of the RCA. The most used catheter shapes were Judkins right (42%) and Amplatz left (25%), and most (56%) catheters were used during percutaneous coronary interventions. Guiding catheters were used in 38% (19/50) of diagnostic procedures when IACD occurred. A catheter size of ≤5F was used in only 3 cases. The catheter size was 6F in 22% of the cases, >6F in 23%, and not reported in 52%. A high-grade dissection (Dunning class III) occurred in 54% (77/142) of the cases. Stenting of the RCA ostium was performed in 88 (62%) of the cases, conservative treatment in 25 (18%), and surgery in 40 (28%) (aortic root repair [5%], coronary artery bypass grafting and aortic root repair [11%], and coronary artery bypass grafting alone [10%]). The mortality rate was 6.5% (5/77) among patients with class III dissection. Each patient should be considered independently. The most frequent intervention was to seal the dissection with a stent in the ostial RCA. However, in select cases published in the literature, a conservative approach was a feasible and successful option.

摘要

医源性主动脉冠状动脉夹层(IACD)主要发生在涉及右冠状动脉(RCA)的手术过程中,可导致残疾、需要紧急进行复杂手术,甚至死亡。IACD的危险因素尚不明确,最佳管理策略也存在疑问;因此,有必要评估RCA发生IACD患者的特征、治疗选择和预后。我们检索了医学数据库,以获取有关RCA的IACD的出版物,以呈现手术特征、管理和预后情况。我们报告了1973年至2021年间报道的142例RCA的IACD病例。患者的平均年龄为63.0岁,81例(57%)为男性,75例(52.8%)表现为稳定型心绞痛,29例(20.4%)RCA慢性完全闭塞。最常用的导管形状是右Judkins导管(42%)和左Amplatz导管(25%),大多数(56%)导管用于经皮冠状动脉介入治疗。IACD发生时,38%(19/50)的诊断性手术使用了引导导管。仅3例使用了≤5F的导管尺寸。22%的病例导管尺寸为6F,23%大于6F,52%未报告。54%(77/142)的病例发生了高级别夹层(邓宁III级)。88例(62%)病例对RCA开口进行了支架置入,25例(18%)进行了保守治疗,40例(28%)进行了手术(主动脉根部修复[5%]、冠状动脉旁路移植术和主动脉根部修复[11%]、单独冠状动脉旁路移植术[10%])。III级夹层患者的死亡率为6.5%(5/77)。应独立考虑每例患者。最常见的干预措施是在RCA开口处用支架封闭夹层。然而,在文献中报道的特定病例中,保守方法是一种可行且成功的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84a/11308116/768b0cb8426e/fx1.jpg

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