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医源性主动脉冠状动脉夹层:管理与结局

Iatrogenic Aortocoronary Dissection: Management and Outcomes.

作者信息

Tulluru Ravi Sankar, Gopinath Karthik, E John Jose, Thomson Viji Samuel, George Ommen K

机构信息

Department of Cardiology, Christian Medical College and Hospital, Vellore, India.

Department of Cardiology, Christian Medical College and Hospital, Vellore, India.

出版信息

JACC Case Rep. 2025 Sep 3;30(26):104888. doi: 10.1016/j.jaccas.2025.104888.

DOI:10.1016/j.jaccas.2025.104888
PMID:40912843
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12426668/
Abstract

BACKGROUND

Iatrogenic aortocoronary dissection (IACD) is a rare but potentially life-threatening complication of percutaneous coronary intervention or diagnostic angiography. The increasing complexity of interventions, especially cases involving chronic total occlusions, calcified lesions, and aggressive balloon dilation, has heightened the risk of IACD. It is often underreported, with an estimated incidence of 0.02% to 0.10%.

CASE PRESENTATION

We present 4 patients with IACD who were managed at our institute in 2024. The right coronary artery was the most frequently involved vessel, and type III IACD was the most common variant. Management strategies included stenting for 50% of patients and conservative management for 50%; no patient required surgical intervention.

CONCLUSIONS

All patients remained stable and were doing well at follow-up. Our case series provides valuable insights into the risk factors, clinical presentation, and management of IACD, highlighting the importance of prevention, early recognition, and tailored treatment strategies to optimize patient outcomes.

摘要

背景

医源性主动脉冠状动脉夹层(IACD)是经皮冠状动脉介入治疗或诊断性血管造影的一种罕见但可能危及生命的并发症。介入治疗的复杂性不断增加,尤其是涉及慢性完全闭塞、钙化病变和积极球囊扩张的病例,增加了IACD的风险。该并发症常报告不足,估计发病率为0.02%至0.10%。

病例介绍

我们报告了2024年在我院接受治疗的4例IACD患者。右冠状动脉是最常受累的血管,III型IACD是最常见的类型。治疗策略包括50%的患者接受支架置入术,50%的患者接受保守治疗;无一例患者需要手术干预。

结论

所有患者在随访时均保持稳定且情况良好。我们的病例系列为IACD的危险因素、临床表现和治疗提供了有价值的见解,强调了预防、早期识别和量身定制治疗策略以优化患者预后的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1c/12426668/b95592d78bdd/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1c/12426668/8a1975b9d515/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1c/12426668/fd7b371d67e9/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1c/12426668/f07a73cf65ac/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1c/12426668/95fd341cb161/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1c/12426668/a42c5c11d6c5/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1c/12426668/97ad7495cacc/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1c/12426668/b95592d78bdd/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1c/12426668/8a1975b9d515/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1c/12426668/fd7b371d67e9/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1c/12426668/f07a73cf65ac/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1c/12426668/95fd341cb161/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1c/12426668/a42c5c11d6c5/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1c/12426668/97ad7495cacc/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1c/12426668/b95592d78bdd/gr7.jpg

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本文引用的文献

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Iatrogenic Aortocoronary Dissection During Right Coronary Artery Procedures: A Systematic Review of the Published Literature.右冠状动脉手术期间医源性主动脉冠状动脉夹层:已发表文献的系统评价
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Catheter-induced coronary artery and aortic dissections. A study of mechanisms, risk factors and propagation causes.导管相关冠状动脉和主动脉夹层。机制、危险因素和传播原因的研究。
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Iatrogenic catheter-induced ostial coronary artery dissections: Prevalence, management, and mortality from a cohort of 55,968 patients over 10 years.
医源性导管所致冠状动脉口夹层:10 年间 55968 例患者的发生率、处理方法和死亡率。
Catheter Cardiovasc Interv. 2021 Oct;98(4):649-655. doi: 10.1002/ccd.29382. Epub 2020 Nov 25.
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Follow-up of iatrogenic aorto-coronary "Dunning" dissections by cardiac computed tomography imaging.通过心脏计算机断层扫描成像对医源性主动脉-冠状动脉“邓宁”夹层进行随访。
BMC Med Imaging. 2017 Dec 21;17(1):64. doi: 10.1186/s12880-017-0227-3.
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Right coronary artery perforation extending to the coronary sinus of Valsalva during percutaneous intervention successfully sealed with polytetrafluoroethylene-covered stent: a case report.经皮介入治疗期间右冠状动脉穿孔延伸至主动脉窦的冠状窦,使用聚四氟乙烯覆膜支架成功封堵:一例病例报告
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Circulation. 2015 Jun 16;131(24):2114-9. doi: 10.1161/CIRCULATIONAHA.115.015334. Epub 2015 Apr 17.
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Guide catheter-induced aortic dissection complicated by pericardial effusion with pulsus paradoxus: a case report of successful medical management.导引导管所致主动脉夹层并心包积液伴奇脉:成功内科治疗 1 例报告
Case Rep Med. 2015;2015:480242. doi: 10.1155/2015/480242. Epub 2015 Jan 1.
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[Structural features of the sinus of valsalva and the proximal portion of the coronary arteries: their relevance to retrograde aortocoronary dissection].[主动脉瓣窦及冠状动脉近端的结构特征:它们与逆行性主动脉冠状动脉夹层的相关性]
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