van Swaaij B W M, Van der Weijden G A, Smith R J, Timmerman M F, Slot D E
Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Department of Dental Hygiene, Hogeschool Arnhem Nijmegen, University of Applied Sciences, Nijmegen, The Netherlands.
Int J Dent Hyg. 2025 Feb;23(1):186-202. doi: 10.1111/idh.12843. Epub 2024 Aug 12.
The primary aim was to systematically assess the available literature on the effect of an essential oils mouthwash without alcohol (EOalc-) compared to an essential oils mouthwash with alcohol (EOalc+) on plaque scores and parameters of gingival health. The secondary aim was to evaluate user appreciation.
The MEDLINE-PubMed and Cochrane-CENTRAL databases were searched to identify eligible studies published up to and including March 2024. Papers comparing the effectiveness of EOalc- and EOalc+ were included. The quality was assessed. A descriptive analysis and a meta-analysis were performed.
After screening, seven papers were found to be eligible. The descriptive analysis demonstrates a significant difference in plaque scores in favour of EOalc+. This is confirmed by the meta-analyses of plaque scores in non-brushing and brushing studies (DiffM = 0.40; 95% CI [0.27; 0.53], p < 0.00001 and DiffM = 0.05; 95% CI [0.01; 0.10], p = 0.01, respectively). This finding is also supported by the sub-analysis of brands. The meta-analyses of bleeding and gingival scores in brushing studies did not show significant differences between products. For user appreciation, the difference found was for taste perception in favour of EOalc- (DiffM = 1.63; 95% CI [0.72; 2.55], p = 0.0004).
When an EO-mouthwash is used in non-brushing or brushing situations, with small to moderate certainty, EOalc- provided less effect regarding plaque control than EOalc+. For bleeding and gingival index there is weak certainty for no difference. In terms of the taste perception EOalc- seems more appreciated.
主要目的是系统评估与含酒精的精油漱口水（EOalc+）相比，不含酒精的精油漱口水（EOalc-）对菌斑评分和牙龈健康参数的影响的现有文献。次要目的是评估用户满意度。
检索MEDLINE-PubMed和Cochrane-CENTRAL数据库，以确定截至2024年3月（含该月）发表的符合条件的研究。纳入比较EOalc-和EOalc+有效性的论文。评估质量。进行描述性分析和荟萃分析。
筛选后，发现七篇论文符合条件。描述性分析表明菌斑评分存在显著差异，有利于EOalc+。非刷牙和刷牙研究中菌斑评分的荟萃分析证实了这一点（DiffM = 0.40；95%CI [0.27；0.53]，p < 0.00001和DiffM = 0.05；95%CI [0.01；0.10]，p = 0.01）。这一发现也得到了品牌亚组分析的支持。刷牙研究中出血和牙龈评分的荟萃分析未显示产品之间存在显著差异。对于用户满意度，发现的差异在于口感方面有利于EOalc-（DiffM = 1.63；95%CI [0.72；2.55]，p = 0.0004）。
当在非刷牙或刷牙情况下使用精油漱口水时，在低至中等确定性水平下，EOalc-在控制菌斑方面的效果不如EOalc+。对于出血和牙龈指数，没有差异的确定性较低。在口感方面，EOalc-似乎更受青睐。
