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含酒精和不含酒精的精油漱口水对菌斑形成的效果:一项随机、交叉、双盲、临床试验。

Efficacy of Essential Oil Mouthwashes With and Without Alcohol on the Plaque Formation: A Randomized, Crossover, Double-Blinded, Clinical Trial.

机构信息

Faculty of Dentistry, University Center of Serra Gaúcha - FSG, Caxias do Sul, RS, Brazil; Faculty of Dentistry, Catholic University of Portugal, Viseu, Portugal; Interdisciplinary Institute of Health Sciences (CIIS), Portugal; Department of Periodontology, Faculty of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.

Faculty of Dentistry, University Center of Serra Gaúcha - FSG, Caxias do Sul, RS, Brazil.

出版信息

J Evid Based Dent Pract. 2021 Mar;21(1):101527. doi: 10.1016/j.jebdp.2021.101527. Epub 2021 Jan 19.

DOI:10.1016/j.jebdp.2021.101527
PMID:34051963
Abstract

BACKGROUND

Essential oil (EO) mouthwash has been considered as one of the effective chemical agents as an adjunct to mechanical plaque control, without adverse effects compared with chlorhexidine (pigmentation, changes of taste, and formation of supragingival calculus), which limits its continuous use. New EO alcohol-based has emerged with questions regarding contraindications for its daily use.

OBJECTIVE

To compare the efficacy of EO mouthwashes with and without alcohol on the early supragingival and subgingival plaque formation using a plaque-free zone score system.

METHODS

This study was a crossover, randomized, double-blind clinical trial. Eleven participants, totaling 396 sites of evaluation, remained 4 days with no mechanical oral hygiene control and only used EO mouthwash with (control) and without alcohol (test) during this period. The presence of the plaque-free zone was recorded every 24 hours. Friedman and Wilcoxon tests were used with a 5% significance level.

RESULTS

The control group showed a more significant number of buccal surfaces free of plaque at 48, 72, and 96 hours compared with the test group. Both groups presented satisfactory efficacy up to 72 hours with a significant difference in favor of the control group. The presence of subgingival plaque on both the proximal and free surfaces was significantly higher in the test group.

CONCLUSION

EO with alcohol presented better results in retarding the early supragingival and subgingival plaque formation compared with EO without alcohol.

摘要

背景

与洗必泰(染色、味觉改变和龈上结石形成)相比,精油(EO)漱口水作为机械菌斑控制的辅助手段之一,没有不良反应,被认为是一种有效的化学制剂,但因其使用受限。新型含酒精的 EO 漱口水已出现,但其每日使用的禁忌问题尚存疑问。

目的

通过菌斑无区评分系统比较含酒精和不含酒精的 EO 漱口水对早期龈上和龈下菌斑形成的效果。

方法

这是一项交叉、随机、双盲临床试验。11 名参与者,共 396 个评估部位,在 4 天内不进行机械口腔卫生控制,仅在这段时间内使用含酒精(对照)和不含酒精(试验)的 EO 漱口水。每 24 小时记录菌斑无区的存在情况。采用 Friedman 和 Wilcoxon 检验,显著性水平为 5%。

结果

与试验组相比,对照组在 48、72 和 96 小时时颊面有更多的无菌斑部位。两组在 72 小时内均表现出令人满意的效果,对照组的效果显著更好。试验组龈下和近中面的菌斑存在明显更高。

结论

与不含酒精的 EO 相比,含酒精的 EO 在延缓早期龈上和龈下菌斑形成方面表现出更好的效果。

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引用本文的文献

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Essential oils mouthwash with or without alcohol in relation to effect on parameters of plaque and gingivitis: A systematic review and meta-analysis.含或不含酒精的精油漱口水对牙菌斑和牙龈炎参数的影响:一项系统评价和荟萃分析。
Int J Dent Hyg. 2025 Feb;23(1):186-202. doi: 10.1111/idh.12843. Epub 2024 Aug 12.
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versus biofilms for evaluating the antimicrobial effectiveness of herbal mouthrinses.用于评估草药漱口液抗菌效果的抗生物膜与生物膜。
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