Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing. No. 1 Dongjiaominxiang Street, Dongcheng District, Beijing 100730, China.
Maternal and Child Health Hospital of Haidian District, Beijing, China.
Photodiagnosis Photodyn Ther. 2024 Oct;49:104305. doi: 10.1016/j.pdpdt.2024.104305. Epub 2024 Aug 10.
To evaluate temporal vascular arcade angle and its influencing factors in myopic children.
It was a retrospective study, we reviewed the records of 119 patients aged 6-10 years with myopia (spherical equivalent refractive error (SER) ≤ -0.05D) in the third year of follow-up in Beijing Hyperopia Reserve Research. We measured temporal vascular arcade angles on the fundus photographs and measured 3-year rate of spherical equivalent(D/year) and axial length (AXL) changes(mm/year).
Mean age at initial visit was 7.71±1.20 years and mean SER was -1.32±1.09D. Children were divided into two groups according to the refractive status of children at baseline: Myopia onset group (SER>-0.50D at baseline) (n = 107) and Myopia progression group (SER≤-0.50D at baseline) (n = 12). The mean SER in Myopia progression group was much smaller than Myopia onset group (P < 0.001) and mean AXL in Myopia progression group was much longer than Myopia onset group (P = 0.042). AXL (r=-0.320, P < 0.001), SER change rate (r=-0.209, P = 0.022) and AXL change rate (r=-0.232, P = 0.011) were associated with temporal vascular arcade angle in all participants. In Myopia onset group, AXL (r=-0.317, P < 0.001) and AXL change rate (r=-0.190, P = 0.05) were associated with temporal vascular arcade angle. There were no parameters were associated with temporal vascular arcade angle (all P > 0.05) in Myopia progression group. Only AXL (r=-0.306, P = 0.018) was associated with temporal vascular arcade angle in girls while AXL (r=-0.370, P = 0.004), SER change rate (r=-0.317, P = 0.013) and AXL change rate (r=-0.365, P = 0.004) were all associated with the Angle in boys.
Temporal vascular arcade angle was associated with the rate of SER and AXL changes in myopia onset children, and showed gender differences. These may suggest that lamina cribrosa location has different influencing factors in different genders and different stages of myopia development. Due to the small number of people in Myopia progression group, large sample size studies are still needed in the future.
评估近视儿童的颞侧血管弓角度及其影响因素。
这是一项回顾性研究，我们对北京远视储备研究中第 3 年随访的 119 名近视（等效球镜屈光度（SER）≤-0.05D）儿童的眼底照片进行了回顾性分析。我们测量了颞侧血管弓角度，并测量了 3 年 SER 变化率（D/年）和眼轴（AXL）变化率（mm/年）。
初次就诊时的平均年龄为 7.71±1.20 岁，平均 SER 为-1.32±1.09D。根据儿童基线时的屈光状态将儿童分为两组：近视起始组（SER>-0.50D 基线）（n=107）和近视进展组（SER≤-0.50D 基线）（n=12）。近视进展组的平均 SER 明显小于近视起始组（P<0.001），近视进展组的平均 AXL 明显长于近视起始组（P=0.042）。所有参与者中，AXL（r=-0.320，P<0.001）、SER 变化率（r=-0.209，P=0.022）和 AXL 变化率（r=-0.232，P=0.011）与颞侧血管弓角度相关。在近视起始组中，AXL（r=-0.317，P<0.001）和 AXL 变化率（r=-0.190，P=0.05）与颞侧血管弓角度相关。在近视进展组中，没有参数与颞侧血管弓角度相关（均 P>0.05）。仅在女孩中，AXL（r=-0.306，P=0.018）与颞侧血管弓角度相关，而在男孩中，AXL（r=-0.370，P=0.004）、SER 变化率（r=-0.317，P=0.013）和 AXL 变化率（r=-0.365，P=0.004）均与角度相关。
颞侧血管弓角度与近视起始儿童 SER 和 AXL 变化率相关，且存在性别差异。这可能表明，在不同性别和不同近视发展阶段，筛板的位置有不同的影响因素。由于近视进展组人数较少，未来仍需要大样本量的研究。
