Department of Respiratory and Critical Care Medicine, No.6th People's Hospital Affiliated to Shanghai Jiao Tong University School, Shanghai 200233, China.
Comput Math Methods Med. 2022 Apr 30;2022:5901552. doi: 10.1155/2022/5901552. eCollection 2022.
To explore the correlations between sleep quality and depression and anxiety in hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).
A total of 131 AECOPD patients treated at No.6th People's Hospital affiliated to Shanghai Jiao Tong University School from January 2018 to December 2020 were selected and divided into the classes I ( = 30), II ( = 23), III ( = 37), and IV ( = 41) based on the severity of AECOPD. The Pittsburgh sleep quality index (PSQI) and the hospital anxiety and depression scale (HADS) were employed to assess the quality of sleep and anxiety/depression in AECOPD patients. The Pearson correlation analysis explored the associations between PSQI score and HADS anxiety/depression score. Binary logistic regression was utilized to determine risk factors for anxiety/depression in AECOPD patients.
The PSQI score, HADS anxiety score, and HADS depression score in patients with AECOPD class III and class IV were significantly higher than those of classes I and II. The severe anxiety and depression ratio were significantly different among patients with classes I-IV AECOPD. The severity of AECOPD was significantly correlated with the PSQI score ( = 0.51, < 0.001), HADS anxiety score ( = 0.66, < 0.001), and HADS anxiety score ( = 0.65, < 0.001). Binary logistic regression analysis showed that the COPD duration, the severity of AECOPD, and PSQI score were the risk factors for anxiety and depression in patients with AECOPD.
Poor sleep quality, anxiety, and depression are common in patients with AECOPD. Improvement of sleep quality may help to alleviate anxiety and depression in AECOPD patients.
探讨慢性阻塞性肺疾病急性加重（AECOPD）住院患者睡眠质量与抑郁、焦虑的相关性。
选取 2018 年 1 月至 2020 年 12 月上海交通大学附属第六人民医院收治的 131 例 AECOPD 患者，根据 AECOPD 严重程度分为 I 级（n = 30）、II 级（n = 23）、III 级（n = 37）和 IV 级（n = 41）。采用匹兹堡睡眠质量指数（PSQI）和医院焦虑抑郁量表（HADS）评估 AECOPD 患者睡眠质量和焦虑/抑郁情况。采用 Pearson 相关性分析探讨 PSQI 评分与 HADS 焦虑/抑郁评分的相关性。采用二项 logistic 回归分析确定 AECOPD 患者焦虑/抑郁的危险因素。
AECOPD Ⅲ级和Ⅳ级患者 PSQI 评分、HADS 焦虑评分和 HADS 抑郁评分均显著高于 I 级和 II 级患者。AECOPD I 级-IV 级患者严重焦虑和抑郁比例差异有统计学意义。AECOPD 严重程度与 PSQI 评分（ = 0.51，< 0.001）、HADS 焦虑评分（ = 0.66，< 0.001）和 HADS 抑郁评分（ = 0.65，< 0.001）显著相关。二项 logistic 回归分析显示，COPD 病程、AECOPD 严重程度和 PSQI 评分是 AECOPD 患者焦虑和抑郁的危险因素。
AECOPD 患者睡眠质量差、焦虑和抑郁较为常见。改善睡眠质量可能有助于缓解 AECOPD 患者的焦虑和抑郁。
