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自限性巨细胞动脉炎:与其诊断和治疗相关的困境

Self-limited Giant Cell Arteritis: The Dilemma Associated with Its Diagnosis and Treatment.

作者信息

Hirose Koki, Kanzawa Yohei, Sano Nobuya, Tsuruta Keishiro, Mizuki Shimpei, Nakajima Takahiro, Ishimaru Naoto, Kinami Saori

机构信息

Department of General Internal Medicine, Akashi Medical Center, Japan.

Department of Pathology, Akashi Medical Center, Japan.

出版信息

Intern Med. 2025 Mar 15;64(6):959-963. doi: 10.2169/internalmedicine.3840-24. Epub 2024 Aug 10.

DOI:10.2169/internalmedicine.3840-24
PMID:39135253
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11986302/
Abstract

Giant cell arteritis (GCA) can result in visual loss and other sequelae. An 81-year-old man presented with a one-week history of fever. He had bilateral temporal headache, jaw claudication, tenderness of the temporal arteries and a recent skin rash. A temporal artery biopsy showed typical GCA, but the symptoms were self-limiting. We continued close observation, without administering prednisolone treatment. Five months later, the symptoms did not recur, and prednisolone again was not administered. Our patient presented with an atypical course of GCA that created a clinical dilemma. The final diagnosis was self-limiting GCA.

摘要

巨细胞动脉炎(GCA)可导致视力丧失和其他后遗症。一名81岁男性,有一周的发热病史。他双侧颞部头痛、咀嚼肌间歇性运动障碍、颞动脉压痛,近期出现皮疹。颞动脉活检显示为典型的GCA,但症状为自限性。我们持续密切观察,未给予泼尼松龙治疗。五个月后,症状未复发,也未再次给予泼尼松龙治疗。我们的患者表现出非典型的GCA病程,造成了临床困境。最终诊断为自限性GCA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaee/11986302/ef9cafd2e7ea/1349-7235-64-0959-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaee/11986302/3f856cd9a666/1349-7235-64-0959-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaee/11986302/1328158f1bff/1349-7235-64-0959-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaee/11986302/f23b7279bd6a/1349-7235-64-0959-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaee/11986302/ef9cafd2e7ea/1349-7235-64-0959-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaee/11986302/3f856cd9a666/1349-7235-64-0959-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaee/11986302/1328158f1bff/1349-7235-64-0959-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaee/11986302/f23b7279bd6a/1349-7235-64-0959-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaee/11986302/ef9cafd2e7ea/1349-7235-64-0959-g004.jpg

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本文引用的文献

1
Vasculitis: When to Consider this Diagnosis?血管炎:何时考虑此诊断?
Med Clin North Am. 2023 Sep;107(5):845-859. doi: 10.1016/j.mcna.2023.05.005. Epub 2023 Jun 17.
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2022 American College of Rheumatology/EULAR classification criteria for giant cell arteritis.2022 年美国风湿病学会/欧洲抗风湿病联盟巨细胞动脉炎分类标准。
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QJM. 2022 Sep 22;115(9):621-622. doi: 10.1093/qjmed/hcac171.
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Mod Rheumatol Case Rep. 2022 Jan 7;6(1):75-79. doi: 10.1093/mrcr/rxab001.
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Diagnosis and management of giant cell arteritis: Major review.巨细胞动脉炎的诊断与治疗:主要综述。
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Clinicopathologic Associations in a Large International Cohort of Patients With Giant Cell Arteritis.大样本国际巨细胞动脉炎患者队列的临床病理关联。
Arthritis Care Res (Hoboken). 2022 Jun;74(6):1013-1018. doi: 10.1002/acr.24540. Epub 2022 Apr 2.
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Autoimmun Rev. 2021 Feb;20(2):102732. doi: 10.1016/j.autrev.2020.102732. Epub 2020 Dec 14.
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Acute visual loss without concurrent headaches due to ultrasound-negative, biopsy-proven giant cell arteritis.
Clin Med (Lond). 2020 Mar;20(Suppl 2):s58. doi: 10.7861/clinmed.20-2-s58.
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JCS 2017 Guideline on Management of Vasculitis Syndrome - Digest Version.《日本循环学会2017年血管炎综合征管理指南 - 摘要版》
Circ J. 2020 Jan 24;84(2):299-359. doi: 10.1253/circj.CJ-19-0773. Epub 2020 Jan 18.