Department of Laboratory Medicine, Seoul National University Bundang Hospital and Seoul National University College of Medicine, Seoul, Republic of Korea.
Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Republic of Korea.
Front Cell Infect Microbiol. 2024 Jul 29;14:1411145. doi: 10.3389/fcimb.2024.1411145. eCollection 2024.
The rapid spread of COVID-19 worldwide within 2 months demonstrated the vulnerability of the world's population to infectious diseases. In 2015, the Global Antimicrobial Resistance and Use Surveillance System (GLASS) was launched to combat antimicrobial resistance (AMR). However, there has been no comprehensive assessment of the decade-long global battle against AMR based on GLASS data.
South Korea established Kor-GLASS (Korean-GLASS) to proactively monitor data quality and enable international collaborations. A unique feature of Kor-GLASS is the quality control center (QCC), which uses network hubs and ensures standardized, high-quality data through interlaboratory proficiency testing (IPT) and external quality assessment (EQA). In addition, the QCC multifaceted endeavors for integrated data quality management.
Since 2020, high-quality AMR data have indicated fluctuating antibiotic resistance rates in South Korea. This trend does not align with the decrease in antibiotic usage seen in humans but coincides with non-human antibiotic sales, indicating a need for greater monitoring of non-human antibiotic resistance. Comprehensive and robust management taking account of the intricate interplay among humans, animals, and the environment is essential. Kor-GLASS has been expanded into a "One Health" multiagency collaborative initiative.
Although a standardized solution is not suitable for all countries, it must align with the local context and international standards. A centralized top-down management structure such as that of the QCC is essential to ensure continuous data quality coordination. Sustained efforts and surveillance systems are crucial for monitoring and managing AMR and safeguarding human health.
COVID-19 在全球范围内的迅速传播在两个月内就表明了全球人口对抗传染病的脆弱性。2015 年，全球抗菌药物耐药性和使用监测系统（GLASS）启动，以对抗抗菌药物耐药性（AMR）。然而，目前还没有基于 GLASS 数据对长达十年的全球 AMR 防控工作进行全面评估。
韩国建立了 Kor-GLASS（韩国-GLASS），以主动监测数据质量并开展国际合作。Kor-GLASS 的一个独特特点是质量控制中心（QCC），它使用网络枢纽，并通过实验室间能力验证（IPT）和外部质量评估（EQA）确保标准化、高质量的数据。此外，QCC 还通过多方努力实现了综合的数据质量管理。
自 2020 年以来，高质量的 AMR 数据表明韩国的抗生素耐药率波动不定。这一趋势与人类抗生素使用量的减少不一致，而是与非人类抗生素销售相吻合，这表明需要加强对非人类抗生素耐药性的监测。全面和强有力的管理需要考虑到人类、动物和环境之间错综复杂的相互作用。Kor-GLASS 已扩展成为一个“同一健康”多机构合作倡议。
尽管标准化解决方案并不适合所有国家，但它必须符合当地情况和国际标准。QCC 等集中式自上而下的管理结构对于确保持续的数据质量协调至关重要。持续的努力和监测系统对于监测和管理 AMR 以及保护人类健康至关重要。
