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创伤性去骨瓣减压术:你需要知道的事。

Decompressive craniectomy in trauma: What you need to know.

机构信息

From the Division of Neurosurgery, Department of Clinical Neurosciences (G.S., J.S., M.M., I.H., A.G.K. P.J.H.), Addenbrooke's Hospital, University of Cambridge, Cambridge; National Hospital for Neurology and Neurosurgery (J.S.), London, United Kingdom; and Neurocenter (I.H.), Department of Neurosurgery, Turku University Hospital, Turku, Finland.

出版信息

J Trauma Acute Care Surg. 2024 Oct 1;97(4):490-496. doi: 10.1097/TA.0000000000004357. Epub 2024 Aug 9.

Abstract

Decompressive craniectomy (DC) is a surgical procedure in which a large section of the skull is removed, and the underlying dura mater is opened widely. After evacuating a traumatic acute subdural hematoma, a primary DC is typically performed if the brain is bulging or if brain swelling is expected over the next several days. However, a recent randomized trial found similar 12-month outcomes when primary DC was compared with craniotomy for acute subdural hematoma. Secondary removal of the bone flap was performed in 9% of the craniotomy group, but more wound complications occurred in the craniectomy group. Two further multicenter trials found that, whereas early neuroprotective bifrontal DC for mild to moderate intracranial hypertension is not superior to medical management, DC as a last-tier therapy for refractory intracranial hypertension leads to reduced mortality. Patients undergoing secondary last-tier DC are more likely to improve over time than those in the standard medical management group. The overall conclusion from the most up-to-date evidence is that secondary DC has a role in the management of intracranial hypertension following traumatic brain injury but is not a panacea. Therefore, the decision to offer this operation should be made on a case-by-case basis. Following DC, cranioplasty is warranted but not always feasible, especially in low- and middle-income countries. Consequently, a decompressive craniotomy, where the bone flap is allowed to "hinge" or "float," is sometimes used. Decompressive craniotomy is also an option in a subgroup of traumatic brain injury patients undergoing primary surgical evacuation when the brain is neither bulging nor relaxed. However, a high-quality randomized controlled trial is needed to delineate the specific indications and the type of decompressive craniotomy in appropriate patients.

摘要

去骨瓣减压术(DC)是一种外科手术,其中一部分颅骨被切除,下面的硬脑膜被广泛打开。在清除创伤性急性硬膜下血肿后,如果大脑膨出或预计在接下来的几天内脑肿胀,通常会进行原发性 DC。然而,最近的一项随机试验发现,原发性 DC 与急性硬膜下血肿开颅术相比,12 个月的结果相似。在开颅组中,有 9%的患者进行了二次去除骨瓣手术,但在去骨瓣组中发生了更多的伤口并发症。另外两项多中心试验发现,尽管早期神经保护性双侧额极 DC 治疗轻度至中度颅内高压并不优于药物治疗,但作为难治性颅内高压的最后手段,DC 可降低死亡率。接受二次最后手段 DC 的患者随着时间的推移更有可能改善,而不是标准药物治疗组。从最新的证据得出的总体结论是,继发性 DC 在创伤性脑损伤后颅内高压的治疗中有一定作用,但并不是万能的。因此,应该根据具体情况决定是否提供这种手术。去骨瓣减压术后,颅骨修复是必要的,但并非总是可行的,尤其是在低收入和中等收入国家。因此,有时会使用允许颅骨瓣“枢轴”或“浮动”的减压性颅骨切除术。在原发性手术清除时大脑既不膨出也不松弛的创伤性脑损伤患者亚组中,减压性颅骨切除术也是一种选择。然而,需要一项高质量的随机对照试验来确定在适当患者中特定的减压性颅骨切除术的适应证和类型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df74/11446508/c5bc0195c308/jt-97-490-g001.jpg

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