Karad Rucha, Teja Vasireddy, Patel Hardik, Bhattacharjee Boudhayan, Mondal Agnibho, Haldar Soumendra Nath, Saha Bibhuti
Department of Infectious Diseases and Advanced Microbiology, School of Tropical Medicine, Kolkata, India.
Am J Trop Med Hyg. 2024 Aug 13;111(4):841-843. doi: 10.4269/ajtmh.24-0271. Print 2024 Oct 2.
Tuberculosis (TB) is an airborne infectious disease caused by Mycobacterium tuberculosis that most commonly affects the lungs. Ocular involvement as part of extrapulmonary TB is noted in around 2-18% of cases of extrapulmonary TB. Any part of the eyes can be affected by the tubercular disease process, and a high index of suspicion is required for accurate diagnosis. Because the location is extrapulmonary, obtaining a proper sample is difficult, and the paucibacillary nature of the disease also makes microbiological detection a diagnostic challenge. Response to antitubercular therapy is usually good, and resolution of clinical features is observed in most cases. Here, we present a case report of a patient presenting with a chalazion-like lesion in the left eyelid that recurred after surgical intervention and did not respond to medical therapy. No history of past TB infection or contact was noted in the patient. An active tubercular lung infection was excluded. On further evaluation, the lesion was microbiologically proven to be of tubercular origin, and the signs and symptoms of the patient completely resolved with proper antitubercular therapy.
结核病(TB)是一种由结核分枝杆菌引起的空气传播传染病,最常累及肺部。作为肺外结核的一部分,眼部受累在约2%至18%的肺外结核病例中可见。眼部的任何部位都可能受到结核病程的影响,准确诊断需要高度的怀疑指数。由于病变位于肺外,获取合适的样本困难,且疾病的少菌性质也使微生物学检测成为诊断挑战。对抗结核治疗的反应通常良好,大多数情况下临床特征会消退。在此,我们报告一例患者,其左眼睑出现睑板腺囊肿样病变,手术干预后复发且药物治疗无效。患者既往无结核感染或接触史。排除了活动性肺结核感染。进一步评估显示,该病变经微生物学证实为结核起源,给予适当的抗结核治疗后,患者的体征和症状完全消退。