School of Medicine (A.F.A., L.T., A.W.K.), University of California San Francisco, San Francisco, CA; Department of Ophthalmology (D.C.A., O.O.I., L.W., R.C.K., B.J.W., S.R.G., M.R.V.), University of California San Francisco, San Francisco, CA.
Eye Contact Lens. 2022 Apr 1;48(4):162-168. doi: 10.1097/ICL.0000000000000859.
To evaluate whether use of an antibiotic improves the efficacy of care for a chalazion or hordeolum.
A cross-sectional retrospective review was performed. All patients treated for a newly diagnosed chalazion or hordeolum at the University of California, San Francisco from 2012 to 2018 were identified. Patients were excluded when clinical notes were inaccessible or there was inadequate documentation of treatment modality or outcome. Patient demographics, setting of initial presentation, treatment modalities, antibiotic use, and outcomes were analyzed.
A total of 2,712 patients met inclusion criteria. Management with an antibiotic was observed in 36.5% of patients. An antibiotic was 1.53 times (95% confidence interval [CI], 1.06-2.22, P=0.025) more likely to be prescribed in emergency or acute care setting for a chalazion. Older age was associated with a higher risk of receiving an antibiotic for a hordeolum (adjusted RR 1.07 per decade, 95% CI, 1.05-1.11, P<0.001). The addition of an antibiotic to conservative measures for a chalazion (adjusted RR, 0.97, 95% CI, 0.89-1.04, P=0.393) or hordeolum (adjusted RR, 0.99, 95% CI, 0.96-1.02, P=0.489) was not associated with an increased likelihood of treatment success.
Although frequently prescribed, an antibiotic is unlikely to improve the resolution of a chalazion or hordeolum.
评估使用抗生素是否能提高对睑板腺囊肿或麦粒肿的治疗效果。
进行了一项横断面回顾性研究。在 2012 年至 2018 年间,加利福尼亚大学旧金山分校对所有新诊断为睑板腺囊肿或麦粒肿的患者进行了治疗。当临床记录无法获取或治疗方式或结果的记录不充分时,患者将被排除在外。分析了患者的人口统计学资料、初次就诊的环境、治疗方式、抗生素的使用情况和治疗结果。
共有 2712 名患者符合纳入标准。在 36.5%的患者中观察到使用了抗生素。在急症或急性护理环境中,抗生素的使用可能性是治疗睑板腺囊肿的 1.53 倍(95%置信区间[CI],1.06-2.22,P=0.025)。年龄较大与接受麦粒肿抗生素治疗的风险较高相关(调整后的 RR 为每十年增加 1.07,95%CI,1.05-1.11,P<0.001)。在保守治疗睑板腺囊肿(调整后的 RR,0.97,95%CI,0.89-1.04,P=0.393)或麦粒肿(调整后的 RR,0.99,95%CI,0.96-1.02,P=0.489)时,添加抗生素并不会增加治疗成功的可能性。
尽管经常被处方,但抗生素不太可能提高睑板腺囊肿或麦粒肿的治愈率。