Department of Radiology, The First Medical Center of the Chinese PLA General Hospital, No.28 Fuxing Road, Beijing, 100853, China.
School of Medicine, Nankai University, Tianjin, China.
Sci Rep. 2024 Aug 13;14(1):18785. doi: 10.1038/s41598-024-68810-z.
To compare the pathological results and long-term survival results of early surgery and surgery after at least one year follow-up for ground-glass component predominant lung adenocarcinoma patients. From January 1, 2013 to August 31, 2017, a total of 279 patients with ground-glass nodules (GGNs) undergoing surgical resection and pathologically proved to be pulmonary adenocarcinoma were included in this study. All patients were divided into early surgery group (ES Group) (210 cases) and surgery after follow-up group (FS Group) (69 cases). Patients in FS group experienced at least one year surveillance. Clinical and imaging features were analyzed by using univariate analysis. After analysis, there was no statistical difference in pathological results and long-term prognosis between the two groups. In the follow-up group, grown GGNs have proved to have more aggressive pathological results. The one-year follow-up may be a feasible management method for patients with ground-glass component predominant GGN.
对比肺腺癌磨玻璃结节成分为主型患者行早期手术与至少随访 1 年后手术的病理结果和长期生存结果。2013 年 1 月 1 日至 2017 年 8 月 31 日，共纳入 279 例行手术切除且术后病理证实为肺腺癌的磨玻璃结节（GGN）患者。所有患者均分为早期手术组（ES 组）（210 例）和随访后手术组（FS 组）（69 例）。FS 组患者经历了至少 1 年的随访。采用单因素分析比较两组患者的临床和影像学特征。分析后，两组患者的病理结果和长期预后无统计学差异。在随访组中，生长的 GGN 具有更具侵袭性的病理结果。对磨玻璃成分为主型 GGN 患者进行 1 年随访可能是一种可行的管理方法。
