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慢性阻塞性肺疾病患者接受无创通气的创新技术的临床证据和技术方面:叙述性综述。

Clinical evidence and technical aspects of innovative technology and monitoring of chronic NIV in COPD: a narrative review.

机构信息

Cardiovascular and Respiratory Physiology, TechMed Centre, University of Twente, Enschede, The Netherlands.

Department of Intensive Care, University Medical Center Utrecht, Utrecht, The Netherlands.

出版信息

Expert Rev Respir Med. 2024 Jul;18(7):513-526. doi: 10.1080/17476348.2024.2384024. Epub 2024 Aug 13.

Abstract

INTRODUCTION

Chronic nocturnal noninvasive ventilation (NIV) improves outcomes in COPD patients with chronic hypercapnic respiratory failure. The aim of chronic NIV in COPD is to control chronic hypercapnic respiratory insufficiency and reduce symptoms of nocturnal hypoventilation, thereby improving quality of life. Chronic NIV care is more and more offered exclusively at home, enabling promising outcomes in terms of patient and caregiver satisfaction, hospital care consumption and cost reduction. Yet, to achieve and maintain optimal ventilation, during adaptation and follow-up, effective feasible (home) monitoring poses a significant challenge.

AREAS COVERED

Comprehensive monitoring of COPD patients receiving chronic NIV requires integrating data from ventilators and assessment of the patient's status including gas exchange, sleep quality, and patient-reported outcomes. The present article describes the physiological background of monitoring during NIV and aims to provide an overview of existing methods for monitoring, assessing their reliability and clinical relevance.

EXPERT OPINION

Patients on chronic NIV are 'ideal' candidates for home monitoring; the advantages of transforming hospital to home care are huge for patients and caregivers and for healthcare systems facing increasing patient numbers. Despite the multitude of available monitoring methods, identifying and characterizing the most relevant parameters associated with optimal patient well-being remains unclear.

摘要

简介

慢性夜间无创通气(NIV)可改善合并慢性高碳酸血症呼吸衰竭的 COPD 患者的预后。COPD 患者接受慢性 NIV 的目的是控制慢性高碳酸血症呼吸功能不全,减少夜间通气不足的症状,从而提高生活质量。慢性 NIV 护理越来越多地专门在家庭中进行,这在提高患者和照护者的满意度、减少医院护理的消耗和降低成本方面带来了有前景的结果。然而,为了实现并维持最佳通气,在适应期和随访期间,有效的可行的(家庭)监测提出了重大挑战。

涵盖领域

对接受慢性 NIV 的 COPD 患者进行全面监测需要整合来自呼吸机的数据,并评估患者的状况,包括气体交换、睡眠质量和患者报告的结果。本文描述了 NIV 期间监测的生理背景,并旨在概述现有的监测方法,评估其可靠性和临床相关性。

专家意见

接受慢性 NIV 的患者是家庭监测的“理想”候选者;将医院护理转变为家庭护理对患者和照护者以及面临患者数量不断增加的医疗保健系统具有巨大优势。尽管有多种可用的监测方法,但确定和描述与最佳患者健康状况相关的最相关参数仍不清楚。

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