Liu Xiuyun, Mu Jingjing, Pang Meijun, Fan Xuehai, Zhou Ziwei, Guo Fang, Yu Kai, Yu Huijie, Ming Dong
State Key Laboratory of Advanced Medical Materials and Devices, Medical School, Tianjin University, Tianjin 300072, China.
Haihe Laboratory of Brain Computer Interaction and Human-Machine Integration, Tianjin 300380, China.
Cyborg Bionic Syst. 2024 Jul 1;5:0135. doi: 10.34133/cbsystems.0135. eCollection 2024.
Idiopathic normal pressure hydrocephalus (iNPH) is a kind of hydrocephalus that is easily to be misdiagnosed with brain atrophy due to the similarity of ventricular dilation and cognitive impairment. In this case, we present an old male patient who was diagnosed with iNPH by multimodality approaches. A 68-year-old male patient, with deteriorated gait, declined cognitive function for at least 3 years and urinary incontinence for 3 months. The doctors suspected him a patient with hydrocephalus or Alzheimer's disease based on his symptoms. We used multimodality diagnostic approaches including brain imaging, cerebrospinal fluid tap test, continuous intracranial pressure monitoring, and infusion study to make the final diagnosis of iNPH. He underwent ventriculoperitoneal shunt surgery and was well recovered. This case demonstrates the efficacy of using multimodality approaches for iNPH diagnosis, which saves patient time and clinical cost, worthy of further promotion.
特发性正常压力脑积水（iNPH）是一种脑积水，由于脑室扩张和认知障碍的相似性，很容易被误诊为脑萎缩。在此病例中，我们介绍了一位通过多模态方法被诊断为iNPH的老年男性患者。一名68岁男性患者，步态恶化、认知功能下降至少3年，并有3个月的尿失禁。医生根据其症状怀疑他患有脑积水或阿尔茨海默病。我们使用了包括脑成像、脑脊液穿刺试验、持续颅内压监测和灌注研究在内的多模态诊断方法，最终诊断为iNPH。他接受了脑室腹腔分流手术，恢复良好。该病例证明了使用多模态方法诊断iNPH的有效性，节省了患者时间和临床成本，值得进一步推广。
