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多囊卵巢综合征(PCOS)在青少年中的流行情况和诊断 - 2023 年有哪些新进展?系统评价。

Prevalence and diagnosis of polycystic ovary syndrome (PCOS) in adolescents - what's new in 2023? Systematic review.

机构信息

Department of Pediatrics and Pediatric Endocrinology, Faculty of Medical Sciences, Medical University of Silesia, Katowice, Poland, Poland.

出版信息

Ginekol Pol. 2024;95(8):643-649. doi: 10.5603/gpl.98849. Epub 2024 Aug 14.

Abstract

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting approximately 5 to 18% of women of reproductive age and 3 to 11% of teenagers. The diagnostic criteria used in adult patients are not suitable for the diagnosis of adolescent patients, because some of the features may be physiological for puberty, so research is still ongoing to improve the criteria for diagnosing PCOS in teenagers. Polycystic ovary syndrome is associated with hormonal and metabolic changes and may predispose to the occurrence of many other diseases, such as obesity, metabolic syndrome, hypertension, type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). Due to the high prevalence of PCOS and the various health problems it brings, it is necessary to select adolescent girls from the risk group, make an efficient diagnosis, start appropriate treatment, and lead the patient through a lifestyle change as soon as possible. Researchers' attention is increasingly focused on patients presenting with PCOS already in their teenage years. In our work, we want to look at the latest reports regarding the prevalence, pathophysiology and diagnosis of PCOS in adolescent girls.

摘要

多囊卵巢综合征(PCOS)是最常见的内分泌紊乱疾病,影响大约 5%至 18%的育龄妇女和 3%至 11%的青少年。用于成年患者的诊断标准并不适用于青少年患者的诊断,因为其中一些特征可能是青春期的生理现象,因此仍在进行研究以改善青少年 PCOS 的诊断标准。多囊卵巢综合征与激素和代谢变化有关,可能容易发生许多其他疾病,如肥胖、代谢综合征、高血压、2 型糖尿病和非酒精性脂肪性肝病(NAFLD)。由于 PCOS 的高患病率及其带来的各种健康问题,有必要从高危人群中选择青春期女孩,进行有效的诊断,开始适当的治疗,并引导患者尽快改变生活方式。研究人员越来越关注已经在青少年时期就出现 PCOS 的患者。在我们的工作中,我们希望查看关于青春期女孩 PCOS 的患病率、病理生理学和诊断的最新报告。

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