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多囊卵巢综合征的最新报告和治疗方法。

The latest reports and treatment methods on polycystic ovary syndrome.

机构信息

Department of Dietary and Nutritional Education, Medical University of Lublin, Lublin, Poland.

Department of Experimental Immunology, Medical University of Lublin, Lublin, Poland.

出版信息

Ann Med. 2024 Dec;56(1):2357737. doi: 10.1080/07853890.2024.2357737. Epub 2024 Jul 4.

Abstract

Polycystic ovary syndrome (PCOS) is an increasingly recognized endocrine disorder. The pathogenesis is not fully known. Polycystic ovary syndrome is still difficult to diagnose correctly, despite simple diagnostic criteria. The aim of the study is to review the current knowledge about PCOS and treatment options for patients with the disease. To explore this topic, publications were reviewed and conclusions drawn from them. The incidence of hyperandrogenism in a patient with PCOS may be as high as 60-80%. Increased androgen levels affect ovulation and menstruation, and also result in hirsutism and acne. Additionally, patients have problems with proper glucose tolerance (insulin resistance), type 2 diabetes, hypertension, cardiovascular diseases and metabolic syndrome. PCOS results in various symptoms in patients. The latest treatment methods were analysed. A standard review of publications in the field of diagnosis and treatment of PCOS, IR and hyperandrogenism was used. Lifestyle, especially diet, deserves special attention due to its ease of use. Sleep quality, physical activity and stress reduction are also important. Diet should be the treatment of first choice. Only if dietary intervention does not bring results, the doctor considers pharmacotherapy. Recently, acupuncture and herbal medicine, vagus nerve stimulation have been used in the treatment of PCOS and regulation of hormone levels. Patients are given supplementation to improve the quality of functioning, but it must be remembered that inappropriate doses or too long use may result in a toxic effect opposite to the therapeutic one. Appropriate diet, physical activity - lifestyle changes are crucial in the treatment of PCOS. Supplementation and pharmaceuticals support treatment. It is mandatory to examine these environmental and lifestyle factors as they not only contribute to the occurrence of the disease but also influence its progression.

摘要

多囊卵巢综合征(PCOS)是一种日益被认识的内分泌疾病。其发病机制尚未完全阐明。尽管有简单的诊断标准,但多囊卵巢综合征仍然难以正确诊断。本研究旨在综述多囊卵巢综合征的现有知识及该疾病患者的治疗选择。为了探讨这一主题,我们对文献进行了回顾,并从中得出结论。多囊卵巢综合征患者的高雄激素血症发生率可能高达 60-80%。高雄激素水平不仅影响排卵和月经,还会导致多毛症和痤疮。此外,患者还存在适当的葡萄糖耐量(胰岛素抵抗)、2 型糖尿病、高血压、心血管疾病和代谢综合征等问题。多囊卵巢综合征会导致患者出现各种症状。分析了最新的治疗方法。采用标准方法对多囊卵巢综合征、IR 和高雄激素血症的诊断和治疗相关文献进行了综述。由于其易于使用,生活方式,特别是饮食,值得特别关注。睡眠质量、身体活动和减轻压力也很重要。饮食应作为治疗的首选。只有在饮食干预没有效果的情况下,医生才会考虑药物治疗。最近,针灸和草药、迷走神经刺激已被用于多囊卵巢综合征的治疗和激素水平的调节。患者会接受补充治疗以改善功能质量,但必须记住,不适当的剂量或过长时间的使用可能会导致与治疗作用相反的毒性作用。适当的饮食、身体活动——生活方式的改变在多囊卵巢综合征的治疗中至关重要。补充剂和药物支持治疗。必须检查这些环境和生活方式因素,因为它们不仅会导致疾病的发生,还会影响其进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ab1/11229724/673b3b6a231d/IANN_A_2357737_F0001_C.jpg

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