Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.
J Infect Dis. 2024 Aug 14;230(Supplement_1):S70-S75. doi: 10.1093/infdis/jiae197.
Powassan virus is a tick-borne flavivirus that can cause severe neuroinvasive disease, with areas of endemicity in the Northeast and Midwest United States, Canada, and Russia. Diagnosis is challenging and relies on a high index of suspicion and choosing the right test based on duration of infection and the patient's immune status. This review covers laboratory testing for Powassan virus, including historical considerations, modern options, and methods being developed in the research space.
波瓦桑病毒是一种蜱传黄病毒，可引起严重的神经侵袭性疾病，其流行地区包括美国东北部和中西部、加拿大和俄罗斯。诊断具有挑战性，依赖于高度怀疑和根据感染持续时间和患者免疫状态选择正确的检测方法。本文综述了波瓦桑病毒的实验室检测，包括历史考虑、现代选择以及研究领域正在开发的方法。
