Department of Internal Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH, 44106, USA.
Curr Cardiol Rep. 2024 Oct;26(10):1145-1151. doi: 10.1007/s11886-024-02111-9. Epub 2024 Aug 14.
To examine the concept of time in target range for blood pressure (BP) management, exploring its calculation methods, implications for patient outcomes, and potential use in patient care.
Recent post-hoc analyses of clinical trials and observational studies highlight the importance of BP time in target range in predicting cardiovascular outcomes. Higher time in target range correlates with reduced risks of major adverse cardiovascular events including heart failure, stroke, myocardial infarction and all-cause mortality. Additionally, longer time in target range decreases the risk of incident atrial fibrillation and risk of developing dementia. BP time in target range is a novel metric offering valuable insights into BP control and its impact on clinical outcomes. Higher time in target range is consistently associated with better cardiovascular outcomes across various patient populations. However, the clinical application of BP time in target range requires further investigation through prospective clinical trials and real-world studies. Integrating wearable devices for continuous BP monitoring could enhance the practical utility of BP time in target range in hypertension management.
探讨血压(BP)管理目标范围内时间的概念,探索其计算方法、对患者结局的影响,以及在患者护理中的潜在用途。
临床试验和观察性研究的事后分析强调了 BP 目标范围内时间在预测心血管结局方面的重要性。更高的目标范围内时间与降低主要不良心血管事件(包括心力衰竭、中风、心肌梗死和全因死亡率)的风险相关。此外,更长的目标范围内时间可降低心房颤动和痴呆发生的风险。BP 目标范围内时间是一种新的指标,提供了对血压控制及其对临床结局影响的宝贵见解。在各种患者群体中,更高的目标范围内时间与更好的心血管结局始终相关。然而,BP 目标范围内时间的临床应用需要通过前瞻性临床试验和真实世界研究进一步研究。整合用于连续血压监测的可穿戴设备可以提高 BP 目标范围内时间在高血压管理中的实际效用。