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人体粪类圆线虫感染。

Human Strongyloides stercoralis infection.

作者信息

Yang Ruibing, Xu Meiyining, Zhang Lichao, Liao Yao, Liu Yuheng, Deng Xiaoyan, Wang Lifu

机构信息

Guangzhou Kingmed Center for Clinical Laboratory, Guangzhou, Guangdong 510320, China.

Department of Parasitology of Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.

出版信息

J Microbiol Immunol Infect. 2025 Apr;58(2):164-179. doi: 10.1016/j.jmii.2024.07.010. Epub 2024 Aug 3.

Abstract

Strongyloides stercoralis is an important soil-transmitted helminth occurring world-wide and affecting 30-100 million people. Because many cases are asymptomatic and sensitive diagnostic methods are lacking, S. stercoralis infection is frequently underdiagnosed. The increasing incidence of autoimmune and wasting diseases and increased use of immunosuppressive agents, as well as the increased use of immunosuppressants and cytotoxic drugs, have increased S. stercoralis infection and their mortality. This review provides information about S. stercoralis epidemiology, life cycle, aetiology, pathology, comorbidities, immunology, vaccines, diagnosis, treatment, prevention, control and makes some recommendations for future prevention and control of this important parasite.

摘要

粪类圆线虫是一种重要的土源性蠕虫,广泛分布于世界各地,感染人数达3000万至1亿。由于许多病例无症状且缺乏敏感的诊断方法,粪类圆线虫感染常常被漏诊。自身免疫性疾病和消耗性疾病的发病率不断上升,免疫抑制剂以及免疫抑制剂和细胞毒性药物的使用增加,导致粪类圆线虫感染及其死亡率上升。本文综述了粪类圆线虫的流行病学、生命周期、病因、病理、合并症、免疫学、疫苗、诊断、治疗、预防和控制等方面的信息,并对该重要寄生虫的未来预防和控制提出了一些建议。

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