Retina Unit, Ophthalmology Department, Pierre-Paul Riquet Hospital, Toulouse University Hospital, Place Baylac, 31059, Toulouse, France.
Clinical Investigation Center, Toulouse University Hospital, Toulouse, France.
Sci Rep. 2024 Aug 14;14(1):18857. doi: 10.1038/s41598-024-69591-1.
Rhegmatogenous retinal detachment (RRD) is a sight-threatening condition with rising global incidence. Identifying factors contributing to seasonal variations in RRD would allow a better understanding of RRD pathophysiology. We therefore performed a retrospective case series study investigating the relationship between RRD occurrence and meteorological factors throughout metropolitan France (the METEO-POC study), particularly the mean temperature over the preceding 10-day period (T-1). Adult patients having undergone RRD surgery and residing in one of the three most populated urban areas of each French region were included (January 2011-December 2018). The study involved 21,166 patients with idiopathic RRD (61.1% males, mean age 59.8-65.1 years). RRD incidence per 100,000 inhabitants increased from 7.79 to 11.81. RRD occurrence was not significantly associated with mean temperature over T-1 in the majority of urban areas (31/36). In a minority of areas (5/36) we observed correlations between RRD incidence and mean temperature over T-1, however these were extremely weak (r = 0.1-0.2; p < 0.05). No associations were found between RRD incidence and secondary outcomes: mean daily temperature over the 10 days prior T-1, minimum/maximum temperatures, rainfall, duration of sunshine, atmospheric pressure, overall radiation, relative humidity, wind speed. Overall, we found no relationships between meteorological parameters and RRD occurrence.
孔源性视网膜脱离（RRD）是一种具有全球发病率上升趋势的致盲性疾病。确定导致 RRD 季节性变化的因素将有助于更好地了解 RRD 的病理生理学。因此，我们进行了一项回顾性病例系列研究，调查了法国大都市地区（METEO-POC 研究）RRD 发生与气象因素之间的关系，特别是前 10 天的平均温度（T-1）。研究纳入了在法国每个地区人口最多的三个城市之一居住并接受 RRD 手术的成年患者（2011 年 1 月至 2018 年 12 月）。该研究涉及 21,166 例特发性 RRD 患者（61.1%为男性，平均年龄 59.8-65.1 岁）。每 10 万居民 RRD 发病率从 7.79 增加到 11.81。在大多数城市（31/36），RRD 发生与 T-1 期间的平均温度之间没有显著相关性。在少数地区（5/36），我们观察到 RRD 发病率与 T-1 期间的平均温度之间存在相关性，但相关性非常弱（r=0.1-0.2；p<0.05）。RRD 发病率与次要结局之间也没有发现相关性：T-1 前 10 天的平均每日温度、最低/最高温度、降雨量、日照时间、大气压力、总辐射、相对湿度、风速。总体而言，我们没有发现气象参数与 RRD 发生之间存在关系。
