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基于 EQ-5D-3L 中国效用评分系统的老年椎体成形术后患者的长期生活质量及其影响因素的回顾性研究。

Long-term quality of life and influencing factors in elderly patients after vertebroplasty based on the EQ-5D-3L Chinese utility scoring system: a retrospective study.

机构信息

Department of Anesthesiology, Affiliated Hospital 2 of Nantong University, Nantong, Jiangsu Province, China.

Department of Anesthesiology, The First People's Hospital of Yancheng, Yancheng, Jiangsu Province, China.

出版信息

BMC Geriatr. 2024 Aug 14;24(1):686. doi: 10.1186/s12877-024-05249-x.

DOI:10.1186/s12877-024-05249-x
PMID:39143487
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11323696/
Abstract

BACKGROUND

The quality of life of elderly patients after vertebroplasty is influenced by various factors. Although the EuroQol 5-Dimension 3-Level (EQ-5D-3L) scale has been widely used to assess quality of life, the factors affecting the long-term postoperative quality of life of elderly vertebroplasty patients in China have not been thoroughly studied.

METHODS

This retrospective study included 519 patients aged 65 years and older who underwent elective vertebroplasty. We collected baseline data from these patients and conducted telephone follow-ups 12 months postoperation to evaluate their EQ-5D-3L health utility scores and EuroQol Visual Analogue Scale (EQ-VAS) scores. Univariate and multivariate linear regression models were used to analyse the factors affecting quality of life.

RESULTS

Of the 519 patients, the majority were female (78.0%), aged 65 to 95 years, with an average age of 75.2 years. Twelve months postoperation, pain/discomfort was the most commonly reported issue for 68.4% of patients. The median EQ-5D-3L health utility score was 0.783, with a range between 0.450 and 0.887; the median EQ-VAS score was 75, ranging from 60 to 85. Multivariate linear regression analysis indicated that older age, hormone use, higher American Society of Anesthesiologists (ASA) grades, nondrinking habits, and low albumin levels were found to be independent risk factors affecting long-term quality of life in elderly patients after vertebroplasty. Additionally, a history of tumours, the number of vertebral compression fractures, and bone mineral density were also crucial influencing factors.

CONCLUSIONS

Based on the use of the EQ-5D-3L Chinese utility scoring system, we evaluated the quality of life of patients aged 65 and above 12 months after vertebroplasty. This study identified several factors related to postoperative quality of life in elderly vertebroplasty patients, providing crucial evidence for further clinical decisions and patient education.

摘要

背景

老年患者椎体成形术后的生活质量受到多种因素的影响。尽管 EuroQol 5 维度 3 水平(EQ-5D-3L)量表已被广泛用于评估生活质量,但中国老年椎体成形术后患者长期术后生活质量的影响因素尚未得到彻底研究。

方法

本回顾性研究纳入了 519 名 65 岁及以上接受择期椎体成形术的患者。我们收集了这些患者的基线数据,并在术后 12 个月进行了电话随访,以评估他们的 EQ-5D-3L 健康效用评分和 EuroQol 视觉模拟量表(EQ-VAS)评分。使用单变量和多变量线性回归模型分析影响生活质量的因素。

结果

在 519 名患者中,大多数为女性(78.0%),年龄 65 至 95 岁,平均年龄为 75.2 岁。术后 12 个月时,68.4%的患者最常报告疼痛/不适。EQ-5D-3L 健康效用评分中位数为 0.783,范围为 0.450 至 0.887;EQ-VAS 评分中位数为 75,范围为 60 至 85。多变量线性回归分析表明,年龄较大、使用激素、较高的美国麻醉医师协会(ASA)分级、不饮酒习惯和低白蛋白水平是影响老年椎体成形术后患者长期生活质量的独立危险因素。此外,肿瘤病史、椎体压缩性骨折数量和骨密度也是重要的影响因素。

结论

基于使用 EQ-5D-3L 中国效用评分系统,我们评估了 12 个月后行椎体成形术的 65 岁及以上患者的生活质量。本研究确定了与老年椎体成形术后患者术后生活质量相关的几个因素,为进一步的临床决策和患者教育提供了重要证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d39/11323696/3092edec266e/12877_2024_5249_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d39/11323696/8ce7296c9252/12877_2024_5249_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d39/11323696/676f4f9d971a/12877_2024_5249_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d39/11323696/3092edec266e/12877_2024_5249_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d39/11323696/8ce7296c9252/12877_2024_5249_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d39/11323696/676f4f9d971a/12877_2024_5249_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d39/11323696/3092edec266e/12877_2024_5249_Fig3_HTML.jpg

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