School of Public Health, Medical College of Soochow University, Suzhou, China.
School of Public Health, Fudan University, 130 Dong An Road, Shanghai, 200032, China.
Qual Life Res. 2021 Oct;30(10):2887-2894. doi: 10.1007/s11136-021-02883-5. Epub 2021 May 24.
To assess the ability of the 3-level EQ-5D (i.e., EQ-5D-3L) in predicting all-cause mortality in older Chinese adults.
The data were from a 5-year longitudinal study, Weitang Geriatric Diseases Study, including 4579 community-dwelling older people in eastern China, with the mean age of 72.5 years at baseline and female being 52.0%. Three multivariable logistic regression models were adopted to assess the associations of the baseline EQ-5D data [i.e., the EQ-5D problems, EQ-5D-3L index score, and EQ-5D visual analog scale (VAS) score] with the 5-year all-cause mortality, adjusting for socio-demographic characteristics, and subsequently, health conditions and lifestyle habits.
A total of 183 participants died over the 5-year study period. A larger proportion of the dead reported problems in physical dimensions (i.e., including three dimensions: mobility, self-care, and usual activities, p < 0.05 for all). The mean EQ-5D index score (0.928) and EQ-VAS score (79.7) of the living were higher than those of the dead (0.915 and 73.2, p < 0.05 for both). In multivariable logistic analyses, the EQ-5D health problems in the physical-related dimensions [odds ratio (OR) 2.16, p < 0.05] and the EQ-VAS score (OR: 0.97, p < 0.001) were associated with the 5-year all-cause mortality when adjusting for socio-demographic characteristics, health conditions, and lifestyle habits.
It appears that the EQ-5D-3L could predict mortality in general older Chinese, which could be used to detect high-risk older individuals in China.
评估 EQ-5D-3L(即 EQ-5D-3L)在预测中国老年人群全因死亡率方面的能力。
本研究数据来自一项为期 5 年的纵向研究——卫塘老年疾病研究,共纳入中国东部地区 4579 名社区居住的老年人,平均年龄为 72.5 岁,女性占 52.0%。采用 3 个多变量逻辑回归模型评估基线 EQ-5D 数据(即 EQ-5D 问题、EQ-5D-3L 指数评分和 EQ-5D 视觉模拟评分)与 5 年全因死亡率的相关性,调整了社会人口统计学特征,随后调整了健康状况和生活方式习惯。
在 5 年的研究期间,共有 183 名参与者死亡。死亡组报告身体维度问题的比例较大(即包括三个维度:行动能力、自理能力和日常活动,p<0.05)。存活组的 EQ-5D 指数评分(0.928)和 EQ-VAS 评分(79.7)均高于死亡组(0.915 和 73.2,p<0.05)。在多变量逻辑分析中,身体相关维度的 EQ-5D 健康问题(比值比[OR]为 2.16,p<0.05)和 EQ-VAS 评分(OR:0.97,p<0.001)与调整社会人口统计学特征、健康状况和生活方式习惯后的 5 年全因死亡率相关。
EQ-5D-3L 似乎可以预测中国一般老年人群的死亡率,可用于检测中国的高危老年个体。