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在中国东部的一项为期 5 年的纵向研究中,EQ-5D-3L 能否预测中国老年人的全因死亡率?

Could the EQ-5D-3L predict all-cause mortality in older Chinese? Evidence from a 5-year longitudinal study in eastern China.

机构信息

School of Public Health, Medical College of Soochow University, Suzhou, China.

School of Public Health, Fudan University, 130 Dong An Road, Shanghai, 200032, China.

出版信息

Qual Life Res. 2021 Oct;30(10):2887-2894. doi: 10.1007/s11136-021-02883-5. Epub 2021 May 24.

Abstract

PURPOSE

To assess the ability of the 3-level EQ-5D (i.e., EQ-5D-3L) in predicting all-cause mortality in older Chinese adults.

METHODS

The data were from a 5-year longitudinal study, Weitang Geriatric Diseases Study, including 4579 community-dwelling older people in eastern China, with the mean age of 72.5 years at baseline and female being 52.0%. Three multivariable logistic regression models were adopted to assess the associations of the baseline EQ-5D data [i.e., the EQ-5D problems, EQ-5D-3L index score, and EQ-5D visual analog scale (VAS) score] with the 5-year all-cause mortality, adjusting for socio-demographic characteristics, and subsequently, health conditions and lifestyle habits.

RESULTS

A total of 183 participants died over the 5-year study period. A larger proportion of the dead reported problems in physical dimensions (i.e., including three dimensions: mobility, self-care, and usual activities, p < 0.05 for all). The mean EQ-5D index score (0.928) and EQ-VAS score (79.7) of the living were higher than those of the dead (0.915 and 73.2, p < 0.05 for both). In multivariable logistic analyses, the EQ-5D health problems in the physical-related dimensions [odds ratio (OR) 2.16, p < 0.05] and the EQ-VAS score (OR: 0.97, p < 0.001) were associated with the 5-year all-cause mortality when adjusting for socio-demographic characteristics, health conditions, and lifestyle habits.

CONCLUSIONS

It appears that the EQ-5D-3L could predict mortality in general older Chinese, which could be used to detect high-risk older individuals in China.

摘要

目的

评估 EQ-5D-3L(即 EQ-5D-3L)在预测中国老年人群全因死亡率方面的能力。

方法

本研究数据来自一项为期 5 年的纵向研究——卫塘老年疾病研究,共纳入中国东部地区 4579 名社区居住的老年人,平均年龄为 72.5 岁,女性占 52.0%。采用 3 个多变量逻辑回归模型评估基线 EQ-5D 数据(即 EQ-5D 问题、EQ-5D-3L 指数评分和 EQ-5D 视觉模拟评分)与 5 年全因死亡率的相关性,调整了社会人口统计学特征,随后调整了健康状况和生活方式习惯。

结果

在 5 年的研究期间,共有 183 名参与者死亡。死亡组报告身体维度问题的比例较大(即包括三个维度:行动能力、自理能力和日常活动,p<0.05)。存活组的 EQ-5D 指数评分(0.928)和 EQ-VAS 评分(79.7)均高于死亡组(0.915 和 73.2,p<0.05)。在多变量逻辑分析中,身体相关维度的 EQ-5D 健康问题(比值比[OR]为 2.16,p<0.05)和 EQ-VAS 评分(OR:0.97,p<0.001)与调整社会人口统计学特征、健康状况和生活方式习惯后的 5 年全因死亡率相关。

结论

EQ-5D-3L 似乎可以预测中国一般老年人群的死亡率,可用于检测中国的高危老年个体。

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