Singh Neetu, Kumar Dileep, Yadav Ganesh, Srivastava Mohit Kishore, Mishra Sudhir Ramkishore, Gupta Anil Kumar, Jauhari Sugandha, Roy Madhumita Singha
Department of Obstetrics and Gynaecology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Department of Physical Medicine and Rehabilitation, King George's Medical University, Lucknow, Uttar Pradesh, India.
J Midlife Health. 2020 Oct-Dec;11(4):224-230. doi: 10.4103/jmh.JMH_107_20. Epub 2021 Jan 21.
Postmenopausal women are at highest risk of developing osteoporosis, since their bone mineral density is reduced due to decrease in estrogen level. Various other physiological, emotional, and psychological changes jeopardize the health of these vulnerable females in total and reduce their quality of life (QoL).
To compare the QoL and bone mass density (BMD) among normal BMD, osteopenic, and osteoporotic postmenopausal women.
A cross-sectional observational study was conducted in the outpatient department of physical medicine and rehabilitation at a tertiary care center of northern India from August 2019 to February 2020.
Baseline sociodemographic characteristics of all postmenopausal women were collected using a quantitative tool. Assessment of QoL was done by pretested and validated QUALEFFO-41 scale. For all the women, a bone mineral densitometry test was performed on the L1-L4 lumbar spine, femoral neck, and forearm by the dual-energy X-ray absorptiometry method.
One-way ANOVA test was used to compare the mean BMD values across the three groups. Determination of predictive factors for QoL was performed using stepwise logistic regression analysis.
Significant differences were noted for the mean values of the three domains, i.e., pain, physical, and social function ( < 0.01). Women with osteoporosis had significantly higher pain scores as compared to others. Among those with osteoporosis, the pain scores have significantly increased gradually as age increases.
Postmenopausal women with osteopenia and osteoporosis have poor QoL as compared to those with normal BMD.
绝经后女性患骨质疏松症的风险最高，因为雌激素水平下降会导致其骨矿物质密度降低。各种其他生理、情感和心理变化会全面危及这些脆弱女性的健康，并降低她们的生活质量（QoL）。
比较骨密度正常、骨量减少和骨质疏松的绝经后女性的生活质量和骨密度（BMD）。
2019年8月至2020年2月在印度北部一家三级护理中心的物理医学与康复门诊进行了一项横断面观察研究。
使用定量工具收集所有绝经后女性的基线社会人口学特征。通过预先测试和验证的QUALEFFO - 41量表对生活质量进行评估。对所有女性采用双能X线吸收法在L1 - L4腰椎、股骨颈和前臂进行骨密度测量。
采用单因素方差分析比较三组的平均骨密度值。使用逐步逻辑回归分析确定生活质量的预测因素。
在疼痛、身体和社会功能这三个领域的平均值上存在显著差异（<0.01）。与其他女性相比，骨质疏松女性的疼痛评分显著更高。在骨质疏松女性中，疼痛评分随着年龄增长显著逐渐增加。
与骨密度正常的绝经后女性相比，骨量减少和骨质疏松的绝经后女性生活质量较差。
