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儿科不锈钢和氧化锆牙冠中白细胞介素-6水平及计数的评估:一项对比研究。

Assessment of Interleukin-6 Levels and Counts in Pediatric Stainless Steel and Zirconia Crowns: A Comparative Study.

作者信息

Saharia Nancy P, Malik Manvi, Jhingan Pulkit, Gulati Nikita, Mathur Shivani

机构信息

Department of Pediatric and Preventive Dentistry, I.T.S. Centre for Dental Studies and Research, Ghaziabad, Uttar Pradesh, India.

Department of Oral Pathology, I.T.S. Centre for Dental Studies and Research, Ghaziabad, Uttar Pradesh, India.

出版信息

Int J Clin Pediatr Dent. 2024 Apr;17(4):395-403. doi: 10.5005/jp-journals-10005-2813.

DOI:10.5005/jp-journals-10005-2813
PMID:39144182
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11320827/
Abstract

BACKGROUND

Pediatric dental crowns play an integral role as they maintain the form and function and prolong the life of the affected tooth. However, placing a crown in the oral cavity creates a new niche for the adhesion of microorganisms that can lead to plaque accumulation, gingival inflammation, and the development of secondary caries, which in the long term might determine the clinical success of the restored tooth. The present study allowed us to assess the changes caused by the full coverage restorations at a clinical, immunological, and microbiological level using enzyme-linked immunosorbent assay (ELISA) and microbial analysis.

MATERIALS AND METHODS

The analysis consisted of a total of 26 children aged 3-10 years. They were divided into two groups, group I ( = 13) children receiving preformed zirconia crowns and group II receiving stainless steel crowns (SSCs). Plaque index (PI) scores, gingival index (GI) scores, and interleukin-6 (IL-6) levels were assessed at baseline and at 45 days of follow-up. The part of the study consisted of 13 preformed zirconia crowns and 13 SSCs which were immersed in artificial saliva containing strains of which were then processed for their microbial analysis.

RESULTS

On mean comparison, preformed zirconia crowns performed superiorly both clinically and immunologically compared to SSCs. Microbial analysis using independent -test revealed that the colony-forming units (CFU) per milliliter was statistically significantly higher for the SSCs, and the mean difference among the groups was statistically significant ( < 0.01).

CONCLUSION

Preformed zirconia crowns can be a relative replacement for SSCs in primary teeth with the advantage of esthetics and superior periodontal health.

HOW TO CITE THIS ARTICLE

Saharia NP, Malik M, Jhingan P, Assessment of Interleukin-6 Levels and Counts in Pediatric Stainless Steel and Zirconia Crowns: A Comparative Study. Int J Clin Pediatr Dent 2024;17(4):395-403.

摘要

背景

儿童牙冠在维持患牙的形态和功能以及延长其使用寿命方面发挥着不可或缺的作用。然而,在口腔中放置牙冠会为微生物的黏附创造一个新的微环境,这可能导致菌斑堆积、牙龈炎症和继发龋的发生,从长远来看,这可能决定修复后牙齿的临床成功率。本研究使我们能够使用酶联免疫吸附测定(ELISA)和微生物分析,在临床、免疫和微生物水平上评估全冠修复所引起的变化。

材料与方法

分析共纳入26名3至10岁的儿童。他们被分为两组,第一组(n = 13)儿童接受预成氧化锆冠,第二组接受不锈钢冠(SSC)。在基线和随访45天时评估菌斑指数(PI)评分、牙龈指数(GI)评分和白细胞介素-6(IL-6)水平。研究的第二部分包括13个预成氧化锆冠和13个SSC,将它们浸入含有变形链球菌菌株的人工唾液中,然后对其进行微生物分析。

结果

平均比较显示,与SSC相比,预成氧化锆冠在临床和免疫方面表现更优。使用独立t检验的微生物分析显示,SSC每毫升的菌落形成单位(CFU)在统计学上显著更高,组间平均差异具有统计学意义(P < .01)。

结论

预成氧化锆冠可以相对替代乳牙中的SSC,具有美观和牙周健康状况更佳的优势。

如何引用本文

Saharia NP, Malik M, Jhingan P, 儿童不锈钢冠和氧化锆冠中白细胞介素-6水平及变形链球菌计数的评估:一项比较研究。《国际临床儿科牙科学杂志》2024;17(4):395 - 403。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2c4/11320827/0ed3a1ba9592/ijcpd-17-4-395-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2c4/11320827/2cfe85e2eed0/ijcpd-17-4-395-g001.jpg
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Evaluation of adhesion of Streptococcus mutans, plaque accumulation on zirconia and stainless steel crowns, and surrounding gingival inflammation in primary molars: randomized controlled trial.
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