Nepomuceno Helene, Abrajano Claire, Chiu Bill
Department of Surgery, Stanford University School of Medicine, United States of America.
Department of Surgery, Stanford University School of Medicine, United States of America.
Int J Surg Case Rep. 2024 Dec;125:110500. doi: 10.1016/j.ijscr.2024.110500. Epub 2024 Oct 23.
Pilonidal disease may present with a draining secondary sinus or granuloma, but the development of these findings is not well-characterized.
Two adolescent males presented with pilonidal disease. The first patient had a gluteal cleft abscess, and an incision and drainage procedure was performed. Although the abscess resolved, the incision site formed a granuloma with intermittent draining wound with granulation tissue. He underwent a pit-picking procedure along with excision of the granuloma. A large amount of hair was also removed from within the pilonidal sinus. The second patient underwent an incision and drainage procedure to treat the pilonidal abscess. The incision site evolved into a granuloma with recurring drainage. A pit-picking procedure was performed, and the granuloma was excised. During the excision, a moderate amount of hair was evacuated from the pilonidal sinus.
Many pilonidal patients present with a granuloma or secondary sinus at the gluteal cleft, but there has been no documentation of the natural history of this development. The role of hair is central to pilonidal disease pathophysiology and is a known factor in foreign body granuloma formation - a cutaneous inflammatory response to endogenous or exogenous material in the dermis that is not broken down readily by macrophages.
Even though the pilonidal abscess was drained with an incision, a granuloma was able to form with recurrent drainage when hair was retained within the pilonidal sinus.
藏毛疾病可能表现为有引流的继发窦道或肉芽肿,但这些表现的发展过程尚未得到充分描述。
两名青少年男性患有藏毛疾病。首例患者有臀裂脓肿,行切开引流术。尽管脓肿已消退,但切口部位形成了肉芽肿,伴有肉芽组织的间歇性引流伤口。他接受了掏毛术并切除了肉芽肿。还从藏毛窦内取出了大量毛发。第二例患者接受切开引流术治疗藏毛脓肿。切口部位演变成了反复引流的肉芽肿。进行了掏毛术并切除了肉芽肿。切除过程中,从藏毛窦内排出了适量毛发。
许多藏毛疾病患者在臀裂处出现肉芽肿或继发窦道,但尚无关于这种发展自然史的文献记载。毛发在藏毛疾病病理生理学中起着核心作用,是异物肉芽肿形成的已知因素——一种对真皮内不易被巨噬细胞分解的内源性或外源性物质的皮肤炎症反应。
尽管通过切开引流了藏毛脓肿,但当毛发残留在藏毛窦内时,仍会形成伴有反复引流的肉芽肿。