Biomedical Engineering Department, Faculty of Engineering and Technology, SRM Institute of Science and Technology, Chennai, Tamil Nadu, India.
Department of Applied Computer Sciences, Applied Computer Science College, King Saud University, Riyadh, Saudi Arabia.
PLoS One. 2024 Aug 15;19(8):e0307571. doi: 10.1371/journal.pone.0307571. eCollection 2024.
The study's primary objectives encompass the following: (i) To implement the object detection of ovarian follicles using you only look once (YOLO)v8 and subsequently segment the identified follicles using a hybrid fuzzy c-means-based active contour technique. (ii) To extract statistical features and evaluate the effectiveness of both machine learning (ML) and deep learning (DL) classifiers in detecting polycystic ovary syndrome (PCOS). The research involved a two different dataset in which dataset1 comprising both normal (N = 50) and PCOS (N = 50) subjects, dataset 2 consists of 100 normal and 100 PCOS affected subjects for classification. The YOLOv8 method was employed for follicle detection, whereas statistical features were derived using Gray-level co-occurrence matrices (GLCM). For PCOS classification, various ML models such as Random Forest (RF), k- star, and stochastic gradient descent (SGD) were employed. Additionally, pre-trained models such as MobileNet, ResNet152V2, and DenseNet121 and Vision transformer were applied for the categorization of PCOS and healthy controls. Furthermore, a custom model named Follicles Net (F-Net) was developed to enhance the performance and accuracy in PCOS classification. Remarkably, the F-Net model outperformed among all ML and DL classifiers, achieving an impressive classification accuracy of 95% for dataset1 and 97.5% for dataset2 respectively in detecting PCOS. Consequently, the custom F-Net model holds significant potential as an effective automated diagnostic tool for distinguishing between normal and PCOS.
(i)使用单阶段 YOLOv8 实现卵巢卵泡的目标检测,然后使用基于混合模糊 C-均值的主动轮廓技术对识别的卵泡进行分割。(ii)提取统计特征,并评估机器学习(ML)和深度学习(DL)分类器在检测多囊卵巢综合征(PCOS)中的有效性。研究涉及两个不同的数据集,其中数据集 1 包含正常(N=50)和 PCOS(N=50)受试者,数据集 2 由 100 个正常和 100 个 PCOS 受影响的受试者组成,用于分类。YOLOv8 方法用于卵泡检测,而使用灰度共生矩阵(GLCM)提取统计特征。对于 PCOS 分类,使用了各种 ML 模型,如随机森林(RF)、k-星和随机梯度下降(SGD)。此外,还应用了预训练模型,如 MobileNet、ResNet152V2 和 DenseNet121 和 Vision transformer,用于 PCOS 和健康对照组的分类。此外,开发了一个名为 Follicles Net(F-Net)的自定义模型,以提高 PCOS 分类的性能和准确性。值得注意的是,F-Net 模型在所有 ML 和 DL 分类器中表现出色,在分别检测数据集 1 和数据集 2 中的 PCOS 时,分别实现了令人印象深刻的 95%和 97.5%的分类准确性。因此,自定义 F-Net 模型作为一种有效的自动诊断工具,具有区分正常和 PCOS 的潜力。