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银屑病患者血脂紊乱的流行病学:2006 年至 2023 年趋势分析。

Epidemiology of lipid disturbances in psoriasis: An analysis of trends from 2006 to 2023.

机构信息

Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China; Institute of Dermatology, Shanghai Academy of Traditional Chinese Medicine, Shanghai, 201203, China.

Institute of Dermatology, Shanghai Academy of Traditional Chinese Medicine, Shanghai, 201203, China.

出版信息

Diabetes Metab Syndr. 2024 Aug;18(8):103098. doi: 10.1016/j.dsx.2024.103098. Epub 2024 Aug 6.

Abstract

INTRODUCTION

A strong link has been established between psoriasis and lipid disturbances; however, no study has systematically examined their global epidemiology.

METHODS

We searched six databases from their inception up to October 1, 2023. Data analysis was conducted using Stata SE 15.1. We performed subgroup, meta-regression, and sensitivity analyses to assess the heterogeneity of the pooled studies.

RESULTS

Our review included 239 studies comprising 15,519,570 participants. The pooled prevalence rate of dyslipidemia among individuals with psoriasis was 38%.

CONCLUSION

Patients with severe psoriasis should undergo screening for lipid abnormalities. This can facilitate the early detection of lipid dysfunction and associated cardiovascular comorbidities.

摘要

简介

银屑病与脂质紊乱之间存在密切关联;然而,尚无研究系统地检测它们的全球流行病学情况。

方法

我们从各数据库的创建之初至 2023 年 10 月 1 日进行了检索。使用 Stata SE 15.1 进行数据分析。我们进行了亚组、meta 回归和敏感性分析,以评估汇总研究的异质性。

结果

我们的综述纳入了 239 项研究,共计 15519570 名参与者。银屑病患者中血脂异常的总体患病率为 38%。

结论

患有严重银屑病的患者应接受脂质异常筛查。这有助于早期发现脂质功能障碍和相关心血管合并症。

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