AVAC, New York, New York, USA.
Genesis Analytics, Nairobi, Kenya.
J Int AIDS Soc. 2024 Aug;27(8):e26346. doi: 10.1002/jia2.26346.
The Dual Prevention Pill (DPP) combines oral pre-exposure prophylaxis (PrEP) with oral contraception (OC) to prevent HIV and pregnancy. Noting the significant role played by the private sector in delivering family planning (FP) services in countries with high HIV burden, high level of private sector OC uptake, and the recent growth in self-care and technology-based private sector channels, we undertook qualitative research in Kenya, South Africa and Zimbabwe to prioritize private sector service delivery approaches for the introduction of the DPP.
Between March 2022 and February 2023, we conducted a literature review and key informant interviews with 34 donors and implementing partners, 19 government representatives, 17 private sector organizations, 13 pharmacy and drug shop representatives, and 12 telehealth agencies to assess the feasibility of DPP introduction in private sector channels. Channels were analysed thematically based on policies, level of coordination with the public sector, data systems, supply chain, need for subsidy, scalability, sustainability and geographic coverage.
Wide geographic reach, ongoing pharmacy-administered PrEP pilots in Kenya and South Africa, and over-the-counter OC availability in Zimbabwe make pharmacies a priority for DPP delivery, in addition to private networked clinics, already trusted for FP and HIV services. In Kenya and South Africa, newer, technology-based channels such as e-pharmacies, telehealth and telemedicine are prioritized as they have rapidly grown in popularity due to nationwide accessibility, convenience and privacy. Findings are limited by a lack of standardized data on service uptake in newer channels and gaps in information on commodity pricing and willingness-to-pay for all channels.
The private sector provides a significant proportion of FP services in countries with high HIV burden yet is an untapped delivery source for PrEP. Offering users a range of access options for the DPP in non-traditional channels that minimize stigma, enhance discretion and increase convenience could increase uptake and continuation. Preparing these channels for PrEP provision requires engagement with Ministries of Health and providers and further research on pricing and willingness-to-pay. Aligning FP and PrEP delivery to meet the needs of those who want both HIV and pregnancy prevention will facilitate integrated service delivery and eventual DPP rollout, creating a platform for the private sector introduction of multipurpose prevention technologies.
双重预防丸(DPP)将口服暴露前预防(PrEP)与口服避孕药(OC)结合在一起,以预防 HIV 和怀孕。注意到私营部门在高 HIV 负担、高水平私营部门 OC 使用率以及自我保健和基于技术的私营部门渠道最近增长的国家提供计划生育(FP)服务方面发挥了重要作用,我们在肯尼亚、南非和津巴布韦进行了定性研究,为 DPP 的推出确定了私营部门服务提供方法。
在 2022 年 3 月至 2023 年 2 月期间,我们对 34 名捐助者和实施伙伴、19 名政府代表、17 个私营部门组织、13 个药房和药店代表以及 12 个远程医疗机构进行了文献回顾和关键知情人访谈,以评估 DPP 在私营部门渠道中推出的可行性。根据政策、与公共部门的协调程度、数据系统、供应链、补贴需求、可扩展性、可持续性和地理覆盖范围,对渠道进行了主题分析。
肯尼亚和南非的药房覆盖范围广泛,正在进行药房管理的 PrEP 试点,津巴布韦的 OC 可在药店购买,这些都使药房成为 DPP 提供的重点,此外还有私营网络诊所,这些诊所已经因其提供 FP 和 HIV 服务而受到信任。在肯尼亚和南非,由于全国范围内的可及性、便利性和隐私性,较新的基于技术的渠道,如电子药房、远程医疗和远程医疗,因其迅速普及而被优先考虑。由于缺乏关于较新渠道服务利用率的标准化数据以及关于所有渠道商品定价和支付意愿的信息差距,调查结果受到限制。
在高 HIV 负担国家,私营部门提供了很大一部分 FP 服务,但尚未成为 PrEP 的一个未开发的提供来源。为 DPP 在非传统渠道中提供一系列用户访问选项,最大限度地减少污名化、增强保密性并提高便利性,可能会增加采用率和延续性。为 PrEP 提供服务做好这些渠道的准备需要与卫生部和提供者接触,并进一步研究定价和支付意愿。将 FP 和 PrEP 提供服务相结合,以满足那些既希望预防 HIV 又希望预防怀孕的人的需求,将促进综合服务提供,并最终推出 DPP,为多用途预防技术的私营部门引入创造一个平台。