Public Health Sciences Division, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA, 98109, USA.
Jhpiego, Nairobi, Kenya.
Curr HIV/AIDS Rep. 2024 Jun;21(3):116-130. doi: 10.1007/s11904-024-00696-y. Epub 2024 Mar 22.
To provide an overview of the current state of HIV pre-exposure prophylaxis (PrEP) delivery via private sector pharmacies globally, to discuss the context-specific factors that have influenced the design and implementation of different pharmacy-based PrEP delivery models in three example settings, and to identify future research directions.
Multiple high- and low-income countries are implementing or pilot testing PrEP delivery via private pharmacies using a variety of delivery models, tailored to the context. Current evidence indicates that pharmacy-based PrEP services are in demand and generally acceptable to clients and pharmacy providers. Additionally, the evidence suggests that with proper training and oversight, pharmacy providers are capable of safely initiating and managing clients on PrEP. The delivery of PrEP services at private pharmacies also achieves similar levels of PrEP initiation and continuation as traditional health clinics, but additionally reach individuals underserved by such clinics (e.g., young men; minorities), making pharmacies well-positioned to increase overall PrEP coverage. Implementation of pharmacy-based PrEP services will look different in each context and depend not only on the state of the private pharmacy sector, but also on the extent to which key needs related to governance, financing, and regulation are addressed. Private pharmacies are a promising delivery channel for PrEP in diverse settings. Countries with robust private pharmacy sectors and populations at HIV risk should focus on aligning key areas related to governance, financing, and regulation that have proven critical to pharmacy-based PrEP delivery while pursuing an ambitious research agenda to generate information for decision-making. Additionally, the nascency of pharmacy-based PrEP delivery in both high- and low-and-middle-income settings presents a prime opportunity for shared learning and innovation.
综述目的:概述全球私营部门药房提供艾滋病毒暴露前预防(PrEP)的现状,讨论在三个示例环境中影响不同基于药房的 PrEP 提供模式设计和实施的具体情况因素,并确定未来的研究方向。
最新发现:多个高收入和低收入国家正在实施或试点通过私营药房提供 PrEP,采用各种适合具体情况的提供模式。目前的证据表明,基于药房的 PrEP 服务需求量大,且普遍被客户和药房供应商所接受。此外,有证据表明,通过适当的培训和监督,药房供应商有能力安全地为接受 PrEP 的客户启动和管理 PrEP。在私营药房提供 PrEP 服务的效果与传统的健康诊所相似,均可实现类似水平的 PrEP 启动和持续使用,但除此之外,还可以接触到传统诊所服务不足的人群(例如,年轻男性;少数族裔),这使得药房在增加整体 PrEP 覆盖率方面具有优势。在每个环境中,基于药房的 PrEP 服务的实施情况都将有所不同,不仅取决于私营药房部门的状况,还取决于与治理、融资和监管相关的关键需求的解决程度。在不同环境中,私营药房是 PrEP 的有前途的提供渠道。拥有健全的私营药房部门和艾滋病毒风险人群的国家应专注于调整与治理、融资和监管相关的关键领域,这些领域已被证明是基于药房的 PrEP 提供的关键,同时追求雄心勃勃的研究议程,为决策提供信息。此外,高收入和中低收入国家的基于药房的 PrEP 提供都处于起步阶段,这为共享学习和创新提供了绝佳机会。