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乌干达经产妇队列中的盆底功能障碍患病率及危险因素

Pelvic floor disorder prevalence and risk factors in a cohort of parous Ugandan women.

作者信息

Vemulapalli Ramya, Ngobi Michael Derrick, Kiweewa Flavia Matovu, Jensen JaNiese Elizabeth, Fleecs Julia Diane, Steffen Haley Alaine, Wendt Linder Hagstrom, Jackson Jay Brooks, Kenne Kimberly Ann

机构信息

University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.

Makerere University-John Hopkins University Research Collaboration, Kampala, Uganda.

出版信息

Int J Gynaecol Obstet. 2025 Jan;168(1):362-368. doi: 10.1002/ijgo.15853. Epub 2024 Aug 15.

Abstract

OBJECTIVES

The aim of this study was to determine the prevalence of pelvic floor disorders (PFDs) and associated risk factors among parous Ugandan women.

METHODS

We performed a cross-sectional study of parous Ugandan women. Demographics and assessment for PFD were obtained. The presence of PFD was defined by participant symptom report, standardized questionnaires, and standard physical examination (pelvic organ prolapse quantification [POP-Q] and cough stress test [CST]).

RESULTS

A total of 159 women were enrolled in the study between June 2022 and June 2023. The median age was 35 years and median parity was 4. Forty-four (28%) women in the cohort reported symptoms of urinary incontinence. No women reported symptoms of pelvic organ prolapse or anal incontinence. Seventy-two (46%) participants had a positive CST and 93 (58.3%) had stage II or greater prolapse based on the POP-Q. Cesarean section was found to have a protective effect for the development of PFD (odds ratio [OR] 0.22, 95% confidence interval [CI] 0.07-0.59, P = 0.004).

CONCLUSION

PFDs are prevalent among parous Ugandan women at rates similar to cohorts in other low- and middle-income countries. Cesarean section seems to be a protective factor against developing PFDs.

摘要

目的

本研究旨在确定乌干达经产妇盆底功能障碍(PFDs)的患病率及相关危险因素。

方法

我们对乌干达经产妇进行了一项横断面研究。获取了人口统计学数据并对PFD进行了评估。PFD的存在通过参与者症状报告、标准化问卷和标准体格检查(盆腔器官脱垂定量[POP-Q]和咳嗽压力试验[CST])来定义。

结果

2022年6月至2023年6月期间,共有159名女性纳入本研究。中位年龄为35岁,中位产次为4次。队列中的44名(28%)女性报告有尿失禁症状。没有女性报告有盆腔器官脱垂或肛门失禁症状。72名(46%)参与者CST呈阳性,93名(58.3%)根据POP-Q有II期或更严重的脱垂。发现剖宫产对PFD的发生有保护作用(比值比[OR]0.22,95%置信区间[CI]0.07 - 0.59,P = 0.004)。

结论

乌干达经产妇中PFDs的患病率与其他低收入和中等收入国家的队列相似。剖宫产似乎是预防PFDs发生的一个保护因素。

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