DU Yue, Wang Ya-Juan
Children's Hospital, Capital Institute of Pediatrics/Peking Union Medical College/Chinese Academy of Medical Sciences, Beijing 100020.
Zhongguo Dang Dai Er Ke Za Zhi. 2024 Aug 15;26(8):871-878. doi: 10.7499/j.issn.1008-8830.2312129.
In recent years, the number of premature births worldwide has been increasing, and their long-term prognoses, particularly the cardiovascular outcomes of preterm individuals in adulthood, have become a growing concern. Adults who were born prematurely are at a higher risk for cardiovascular diseases, which may be related to changes in cardiovascular structure, renal structure alterations, changes in body composition, and overactivation of the hypothalamic-pituitary-adrenal axis. To improve the outcomes for preterm individuals, long-term follow-up monitoring and effective prevention and treatment measures are necessary. This article aims to review the relevant literature, summarize the risks and mechanisms of hypertension during childhood and adulthood in those born prematurely, and enhance awareness and understanding of the risk of hypertension in adults who were born prematurely.
近年来,全球早产的数量一直在增加,其长期预后,尤其是早产个体成年后的心血管结局,已成为日益受到关注的问题。早产出生的成年人患心血管疾病的风险更高,这可能与心血管结构变化、肾脏结构改变、身体成分变化以及下丘脑 - 垂体 - 肾上腺轴过度激活有关。为改善早产个体的结局,长期随访监测以及有效的预防和治疗措施是必要的。本文旨在综述相关文献,总结早产个体儿童期和成年期高血压的风险及机制,并提高对早产出生的成年人高血压风险的认识和理解。