Yelich Allyson, Jenkins Hannah, Holt Sara, Miller Richard
Drs. Yelich, Holt, and Miller are with the HCA Healthcare/USF Morsani College of Medicine GME at HCA Florida Largo Hospital, Department of Dermatology in Largo, Florida.
Ms. Jenkins was with Bay Dermatology and Cosmetic Surgery in Largo, Florida, and she is currently affiliated with the College of Osteopathic Medicine, Lake Erie College of Osteopathic Medicine in Bradenton, Florida.
J Clin Aesthet Dermatol. 2024 Aug;17(8):56-61.
Biotin has widespread popularity as a hair supplement. We sought to review the literature regarding biotin's efficacy as a hair supplement.
We conducted a literature search of PubMed for articles specifically studying the use of oral biotin for hair growth or quality. Case reports and case series were excluded.
Three studies met our inclusion criteria. The first study was the highest quality, with a double-blind and placebo-controlled study design, but their results found no difference between the biotin and placebo groups for hair growth. The other two studies investigated specific patient populations (patients on isotretinoin and female patients post-sleeve gastrectomy). Both studies were susceptible to multiple potential biases and neither had striking results in favor of biotin.
Our review is limited by lack of available studies.
Given the widespread popularity of biotin as a hair supplement, one would presume that this claim must be grounded in strong evidence; however, there is a large discrepancy between the public's perception of its efficacy and the scientific literature. The utility of biotin as a hair supplement is not supported by high-quality studies.
生物素作为一种头发补充剂广受欢迎。我们试图回顾关于生物素作为头发补充剂功效的文献。
我们在PubMed上进行文献检索，查找专门研究口服生物素对头发生长或发质影响的文章。排除病例报告和病例系列。
三项研究符合我们的纳入标准。第一项研究质量最高，采用双盲和安慰剂对照研究设计，但其结果发现生物素组和安慰剂组在头发生长方面没有差异。另外两项研究调查了特定患者群体（服用异维A酸的患者和袖状胃切除术后的女性患者）。这两项研究都容易受到多种潜在偏倚的影响，且均未得出明显支持生物素的结果。
我们的综述受到可用研究缺乏的限制。
鉴于生物素作为头发补充剂广受欢迎，人们可能会认为这种说法一定有强有力的证据支持；然而，公众对其功效的认知与科学文献之间存在很大差异。高质量研究并不支持生物素作为头发补充剂的效用。
