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埃塞俄比亚一家综合专科医院术后恶心呕吐的患病率及相关因素

Prevalence and Factors Associated with Postoperative Nausea and Vomiting in an Ethiopian Comprehensive Specialized Hospital.

作者信息

Teshome Diriba, Hunie Metages, Kibret Simegnew, Mestofa Marifa, Fenta Efrem

机构信息

Department of Anesthesia, School of Medicine, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.

出版信息

Adv Prev Med. 2024 Feb 16;2024:6699732. doi: 10.1155/2024/6699732. eCollection 2024.

Abstract

BACKGROUND

Postoperative nausea and vomiting (PONV) is a common and uncomfortable anesthetic and surgical consequences. It may cause severe distress to the patient and may cause the recovery process to be delayed. Identifying the reasons may aid in reducing the magnitude and problems. The purpose of this study was to determine the prevalence and risk factors for PONV after general anesthesia in an Ethiopian hospital.

METHODS

From March 1 to May 30, 2019, a cross-sectional study was designed. A patient interview was used to obtain data on the occurrence of PONV, and a chart review was used to collect data on other demographic and clinical variables. To identify associated factors, variables with a -value of 0.2 in binary logistic regression were transformed into a multivariable logistic regression. The strength of the association and level of significance waswere demonstrated using crude and adjusted odds ratios with 95% confidence intervals and -values of 0.05.

RESULTS

The study included 162 participants, with a remarkable 100% response rate. Within 24 hr after surgery, 51.2% of patients had nausea and vomiting. When compared to their counterparts, female patients, patients who received perioperative opioid medication, patients with a history of PONV, and patients with a history of motion sickness reported a statistically significant difference (higher incidence) in PONV.

CONCLUSION

This study only comprised ASA physical classes 1 and 2 patients who did not receive preventive antiemetics. In the research area, the total prevalence of vomiting and nausea was 51.2%. Female sex, perioperative opioid usage, a history of nausea and vomiting, and a history of motion sickness were discovered to be statistically significantly associated with a higher incidence of PONV.

摘要

背景

术后恶心呕吐(PONV)是一种常见且令人不适的麻醉和手术并发症。它可能给患者带来严重困扰,并可能导致恢复过程延迟。找出原因有助于减轻其严重程度和相关问题。本研究的目的是确定埃塞俄比亚一家医院全身麻醉后PONV的患病率及危险因素。

方法

2019年3月1日至5月30日,设计了一项横断面研究。通过患者访谈获取PONV发生情况的数据,并通过查阅病历收集其他人口统计学和临床变量的数据。为确定相关因素,将二元逻辑回归中P值为0.2的变量转化为多变量逻辑回归。使用粗比值比和调整后的比值比以及95%置信区间和P值为0.05来证明关联强度和显著性水平。

结果

该研究纳入了162名参与者,应答率高达100%。术后24小时内,51.2%的患者出现恶心呕吐。与对照组相比,女性患者、接受围手术期阿片类药物治疗的患者、有PONV病史的患者以及有晕动病史的患者在PONV方面存在统计学显著差异(发生率更高)。

结论

本研究仅纳入了未接受预防性止吐药的ASA身体状况1级和2级患者。在研究区域,恶心和呕吐的总患病率为51.2%。发现女性、围手术期使用阿片类药物、恶心呕吐病史和晕动病史与PONV的较高发生率在统计学上显著相关。

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