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使用瑞马唑仑进行全静脉麻醉用于经颈动脉途径经导管主动脉瓣置换术:一例报告

Total Intravenous Anesthesia Using Remimazolam for Transcarotid Approach Transcatheter Aortic Valve Replacement: A Case Report.

作者信息

Kitaura Atsuhiro, Sakamoto Hiroatsu, Tsukimoto Shota, Yuasa Haruyuki, Nakajima Yasufumi

机构信息

Anesthesiology, Kindai University, Osaka, JPN.

Dental Anesthesiology, Kanagawa Dental University, Yokosuka, JPN.

出版信息

Cureus. 2024 Jul 16;16(7):e64628. doi: 10.7759/cureus.64628. eCollection 2024 Jul.

DOI:10.7759/cureus.64628
PMID:39149680
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11326771/
Abstract

The transcarotid approach was introduced in Japan in April 2024 as an alternative approach for transcatheter aortic valve replacement (TAVR). Because carotid artery blood flow is reduced on one side during the procedure, there is a risk of intraoperative brain stroke. Therefore, it is crucial to check for cerebral complications immediately after the procedure. We report a case involving an 87-year-old female who underwent transcarotid TAVR under general anesthesia with remimazolam and remifentanil. The operation was completed in a short period. There was no evidence of hypotension during the induction of anesthesia, and intraoperative blood pressure control was easy. However, there was a decrease in local oxygen saturation for approximately nine minutes intraoperatively. Following the administration of flumazenil, the patient was quickly awakened, and neurological findings were confirmed to be normal. The patient was discharged without complications. Our findings suggest that remimazolam, an ultra-short-acting benzodiazepine, is feasible for the transcarotid TAVR procedure due to its minimal circulatory impact and ability to facilitate rapid and reliable arousal.

摘要

经颈动脉途径于2024年4月在日本被引入,作为经导管主动脉瓣置换术(TAVR)的一种替代途径。由于在手术过程中一侧颈动脉血流减少,存在术中脑卒的风险。因此,术后立即检查脑部并发症至关重要。我们报告一例87岁女性患者,在使用瑞马唑仑和瑞芬太尼全身麻醉下接受经颈动脉TAVR手术。手术在短时间内完成。麻醉诱导期间无低血压证据,术中血压控制容易。然而,术中局部氧饱和度下降约9分钟。给予氟马西尼后,患者迅速苏醒,神经学检查结果证实正常。患者无并发症出院。我们的研究结果表明,超短效苯二氮䓬类药物瑞马唑仑对经颈动脉TAVR手术是可行的,因为它对循环影响极小,且能够促进快速可靠的苏醒。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb28/11326771/eb29381ae888/cureus-0016-00000064628-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb28/11326771/bc7bd8cd85f2/cureus-0016-00000064628-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb28/11326771/b130dc8b3c08/cureus-0016-00000064628-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb28/11326771/f214da7b11db/cureus-0016-00000064628-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb28/11326771/6be4a0236ea0/cureus-0016-00000064628-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb28/11326771/eb29381ae888/cureus-0016-00000064628-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb28/11326771/bc7bd8cd85f2/cureus-0016-00000064628-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb28/11326771/b130dc8b3c08/cureus-0016-00000064628-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb28/11326771/f214da7b11db/cureus-0016-00000064628-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb28/11326771/6be4a0236ea0/cureus-0016-00000064628-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb28/11326771/eb29381ae888/cureus-0016-00000064628-i05.jpg

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本文引用的文献

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Cardiovasc Revasc Med. 2024 Nov;68:92-97. doi: 10.1016/j.carrev.2024.04.008. Epub 2024 Apr 4.
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Effectiveness of remimazolam in preventing postoperative delirium in elderly patients with proximal femoral fractures.瑞马唑仑预防老年股骨近端骨折患者术后谵妄的有效性。
J Anesth. 2024 Aug;38(4):475-482. doi: 10.1007/s00540-024-03339-z. Epub 2024 Mar 26.
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A retrospective comparative study of anesthesia with remimazolam and remifentanil versus dexmedetomidine and remifentanil for transcatheter aortic valve replacement.
瑞马唑仑和瑞芬太尼与右美托咪定和瑞芬太尼用于经导管主动脉瓣置换术的麻醉的回顾性比较研究。
Sci Rep. 2023 Oct 10;13(1):17074. doi: 10.1038/s41598-023-43895-0.
4
Network Meta-Analysis Comparing the Short- and Long-Term Outcomes of Alternative Access for Transcatheter Aortic Valve Replacement.比较经导管主动脉瓣置换术不同入路短期和长期结果的网状Meta分析
Cardiovasc Revasc Med. 2022 Jul;40:1-10. doi: 10.1016/j.carrev.2021.11.040. Epub 2021 Dec 3.
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STS-ACC TVT Registry of Transcatheter Aortic Valve Replacement.经导管主动脉瓣置换术的STS-ACC TVT注册研究
J Am Coll Cardiol. 2020 Nov 24;76(21):2492-2516. doi: 10.1016/j.jacc.2020.09.595.
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Transcarotid Versus Subclavian/Axillary Access for Transcatheter Aortic Valve Replacement With SAPIEN 3.经颈动脉途径与经锁骨下动脉/腋动脉途径行经导管主动脉瓣置换术治疗 SAPIEN 3 瓣膜的比较。
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J Anesth. 2020 Aug;34(4):543-553. doi: 10.1007/s00540-020-02788-6. Epub 2020 May 16.
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