Department of Dentistry, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University, Galați, România, Galați, Romania.
Department of Basic and Clinical Sciences, Psychiatry University of Nicosia Medical School, Nicosia, Cyprus.
Dialogues Clin Neurosci. 2024;26(1):53-55. doi: 10.1080/19585969.2024.2392491. Epub 2024 Aug 16.
Antidiabetic drugs, reduction of carbohydrates intake, maintaining normal weight and physical activity are the cornerstone of diabetes 2 treatment.
This opinion article is not intended to challenge hundreds of studies unequivocally demonstrating the benefits of a healthy lifestyle including appropriate diet in controlling the consequences of T2DM. The article questions whether the benefits of dietary restrictions for the management of T2D in older adults who are already demented, are worth the potential detrimental effects on quality of life for the patients and their caregivers, as well as the effects of dietary restrictions on frailty, sarcopenia.
However, the benefit of dietary restrictions including carbohydrates restrictions, might not manifest in elderly Alzheimer and vascular dementia patients with type 2 diabetes. On the contrary, such restrictions might hinder the patients' and caregiver's quality of life and encumber attempts to maintain normal weight in a population which tends to be underweight. Therefore, the benefit/risk ratio of dietary restriction should be weighed in this population on an individual basis.
糖尿病 2 型的治疗基石包括使用降糖药物、减少碳水化合物摄入、维持正常体重和进行身体活动。
本文并非旨在质疑数以百计的研究结果，这些研究明确表明健康的生活方式（包括适当的饮食）对控制 2 型糖尿病的后果有益。本文质疑对于已经痴呆的老年 2 型糖尿病患者，饮食限制管理是否值得患者及其照护者的生活质量受到潜在的不利影响，以及饮食限制对虚弱、肌肉减少症的影响。
然而，包括碳水化合物限制在内的饮食限制可能不会使患有阿尔茨海默病和血管性痴呆的老年 2 型糖尿病患者受益。相反，这种限制可能会妨碍患者和照护者的生活质量，并阻碍试图在体重偏轻的人群中保持正常体重。因此，应该在个体基础上权衡饮食限制的获益/风险比。
