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首份关于美洲大陆猪细小病毒 8 型(PPV8)的报告与哥伦比亚患有猪呼吸道疾病的猪有关。

The first report of porcine parvovirus 8 (PPV8) on the American continent is associated with pigs in Colombia with porcine respiratory disease.

机构信息

Universidad Nacional de Colombia, Sede Bogotá, Facultad de Medicina Veterinaria y de Zootecnia, Centro de Investigación en Infectología e Inmunología Veterinaria (CI3V), Carrera 30 # 45-03, Bogotá, D.C, Colombia.

出版信息

Arch Virol. 2024 Aug 16;169(9):179. doi: 10.1007/s00705-024-06099-z.

Abstract

Seven novel porcine parvoviruses (PPV2 to PPV8) have been discovered in the last two decades. The last one reported was PPV8 in China in 2022, which was proposed to be a member of the genus Protoparvovirus. Here, we report the first detection of PPV8 outside China - in two provinces from Colombia. Six out of 146 (4.1%) pigs showing porcine respiratory disease (PRD) tested positive for PPV8. Sequencing and phylogenetic analysis of two Colombian PPV8 isolates (GenBank database accession numbers PP335559 and PP335560) showed them to be members of the genus Protoparvovirus. Furthermore, PPV8 was detected in coinfections with porcine circovirus type 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV), which are associated with PRD.

摘要

在过去的二十年中,已经发现了七种新型猪细小病毒(PPV2 至 PPV8)。最近报道的一种是 2022 年在中国发现的 PPV8,它被提议为原细小病毒属的一个成员。在这里,我们报告了首例在中国以外地区——哥伦比亚两个省份检测到 PPV8。在 146 头表现为猪呼吸道疾病(PRD)的猪中,有 6 头检测到 PPV8 呈阳性。对两株哥伦比亚 PPV8 分离株(GenBank 数据库登录号 PP335559 和 PP335560)的测序和系统发育分析表明,它们属于原细小病毒属。此外,还在与猪圆环病毒 2 型(PCV2)和猪繁殖与呼吸综合征病毒(PRRSV)的混合感染中检测到了 PPV8,这些病毒与 PRD 有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cdc/11329616/b2b6dcc9ccc8/705_2024_6099_Fig1_HTML.jpg

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